Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | 4565 Gaynor Ave, North Charleston | CheapestFastest |
Last refresh of the prices: Yesterday at 10:41 PM EST.
Compare 2 ways to go from Orlando to Charleston
Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 7 hours 49 minutes and with fares starting at just $63, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Charleston?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Orlando to Charleston, SC, US by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Charleston, SC, US was searched and found on Nov 18, 2025 with a price of $42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Charleston, SC, US, as early as possible.
You can expect to pay from $42 to $75 for a bus ticket from Orlando to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-11-21.
What's the cheapest way to go from Orlando to Charleston, SC, US?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
People from around the world trust Busbud
Popular bus departures from Orlando
- Find bus tickets from Orlando to West Palm Beach
- Orlando to Tampa bus times and fares
- How to travel from Orlando to Boca Raton
- Find bus tickets from Orlando to Gainesville
- Orlando to Fort Lauderdale bus times and fares
- How to travel from Orlando to Atlanta
- Find bus tickets from Orlando to Tallahassee
- Orlando to New York City bus times and fares
- How to travel from Orlando to Miami
Popular bus routes to Charleston
- Find bus tickets from Savannah to Charleston
- Jacksonville to Charleston bus times and fares
- How to travel from Philadelphia to Charleston
- Find bus tickets from New York City to Charleston
- Atlanta to Charleston bus times and fares
- How to travel from Newark to Charleston
- Find bus tickets from Boston to Charleston