Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | Durham Greyhound Bus Station | No tags | ||||
 | Bus | 2301 W Lucas St. | BP Gas Station | No tags | ||||
| Bus | 2301 W Lucas St. | BP Gas Station | No tags | ||||
 | Bus | Florence, SC | Durham Greyhound Bus Station | No tags | ||||
| Bus | Bus station | Durham Greyhound Bus Station | No tags |
Compare 2 ways to go from Florence to Durham
Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 4 hours 45 minutes and with fares starting at just $53, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Durham?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Compare bus companies
Frequently asked questions about traveling from Florence, SC, US to Durham, NC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Durham?
The cheapest bus tickets from Florence to Durham start from $53. The average price for this route is around $67. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Durham?
The average bus trip duration from Florence to Durham is 4h 45m, covering a distance of 134 miles (216 km). The quickest bus can get you there in 3h 30m and is operated by Wanda Coach.
Which bus companies service the Florence to Durham route?
Several major bus companies operate on this route with 4 buses available per day, including services from Wanda Coach, FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Florence to Durham?
The earliest bus departs from Florence to Durham at 12:05am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Florence to Durham?
A bus trip from Florence to Durham generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Durham?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Florence to Durham?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Durham?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Durham?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Durham, NC, US was searched and found on Dec 13, 2025 with a price of $60To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Durham, NC, US, as early as possible.
What's the cheapest way to go from Florence, SC, US to Durham, NC, US?
The bus is the cheapest travel choice for this destination
