Bus from Greenville, SC to New Orleans: Tickets & Schedules

Next bus departures

Next departures for Greenville to New Orleans on December 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
New Orleans Bus StationCheapestFastest
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
New Orleans Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
New Orleans Bus StationNo tags
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
New Orleans Intl Airport, 900 Airline DrNo tags

Last refresh of the prices: Last Saturday at 5:58 PM EST.

Compare 2 ways to go from Greenville to New Orleans

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach New Orleans. The journey takes about 15 hours 45 minutes and with fares starting at just $82, it presents an excellent value for a comfortable ride.

3bus per day
15h 45mAverage Duration
564 milesDistance
23kgCO₂ emissions
Average Price$82 - $276Average Duration15h 45m
23kg CO₂e
Average Price$134 - $806Average Duration16h 41m
82kg CO₂e

Frequently asked questions about traveling from Greenville, SC to New Orleans by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to New Orleans?

    The cheapest bus tickets from Greenville to New Orleans start from $82. The average price for this route is around $137. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to New Orleans?

    The average bus trip duration from Greenville to New Orleans is 15h 45m, covering a distance of 564 miles (910 km). The quickest bus can get you there in 13h 55m and is operated by FlixBus.

  3. Which bus companies service the Greenville to New Orleans route?

    Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Greenville to New Orleans?

    The earliest bus departs from Greenville to New Orleans at 2:45pm. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to New Orleans?

    A bus trip from Greenville to New Orleans generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Greenville to New Orleans?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to New Orleans?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Greenville to New Orleans?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to New Orleans?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/07
$126
12/08
$142
Today
$122
12/10
$131
12/11
$112
12/12
$114
12/13
$111
12/14
$83
busbud logoThe cheapest trip from Greenville, SC to New Orleans was searched and found on Dec 14, 2025 with a price of $83

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to New Orleans, as early as possible.

You can expect to pay from $83 to $143 for a bus ticket from Greenville, SC to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at $83 which is on 2025-12-14.

What's the cheapest way to go from Greenville, SC to New Orleans?

busbud logoThe bus is the cheapest travel choice for this destination

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