How much is the bus ticket from Greenville to Philadelphia?

The cheapest bus tickets from Greenville to Philadelphia start from $76. The average price for this route is around $127. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Greenville to Philadelphia?

The average bus trip duration from Greenville to Philadelphia is 20h 15m, covering a distance of 526 miles (849 km). The quickest bus can get you there in 13h 45m and is operated by FlixBus .

Which bus companies service the Greenville to Philadelphia route?

Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Greenville to Philadelphia?

The earliest bus departs from Greenville to Philadelphia at 7:25am. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Greenville to Philadelphia?

A bus trip from Greenville to Philadelphia generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Greenville to Philadelphia?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11380 reviews.

Which bus company has the best Wi-Fi from Greenville to Philadelphia?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Greenville to Philadelphia?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Greenville to Philadelphia?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Greenville to Philadelphia from $78 | Refundable Tickets

Next bus departures

Next departures for Greenville to Philadelphia on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:00pm	1116 Woodruff Rd	21h 5m	7:05pm	Cherry Hill Mall	Cheapest
	Bus	10:00pm	1116 Woodruff Rd	13h 45m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
	Bus	7:25am	1116 Woodruff Rd	20h 20m	3:45am	199 Spring Garden St.	No tags
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	14h 30m	6:45am	199 Spring Garden St.	No tags
	Bus	12:05pm	1116 Woodruff Rd	14h 10m	2:15am	Philadelphia, 199 Spring Garden St	No tags

Next departures for Greenville to Philadelphia on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	14h 30m	6:45am	199 Spring Garden St.	Cheapest
	Bus	10:00pm	1116 Woodruff Rd	13h 45m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
	Bus	7:25am	1116 Woodruff Rd	20h 20m	3:45am	199 Spring Garden St.	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	17h 5m	3:05pm	199 Spring Garden St.	No tags
	Bus	12:05pm	1116 Woodruff Rd	14h 10m	2:15am	Philadelphia, 199 Spring Garden St	No tags

Next departures for Greenville to Philadelphia on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:25am	1116 Woodruff Rd	16h 55m	12:20am	Philadelphia, 199 Spring Garden St	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	14h 30m	6:45am	199 Spring Garden St.	Fastest
	Bus	7:25am	1116 Woodruff Rd	20h 20m	3:45am	199 Spring Garden St.	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	17h 5m	3:05pm	199 Spring Garden St.	No tags
	Bus	4:15pm	1116 Woodruff Rd	16h 30m	8:45am	Philadelphia, 199 Spring Garden St	No tags

Next departures for Greenville to Philadelphia on December 9
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:00pm	1116 Woodruff Rd	22h 35m	8:35pm	Frazer - 56-40 Matthews Rd	Cheapest
	Bus	7:25am	1116 Woodruff Rd	14h 45m	10:10pm	Schuylkill & Walnut	Fastest
	Bus	7:25am	1116 Woodruff Rd	20h 20m	3:45am	199 Spring Garden St.	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	17h 5m	3:05pm	199 Spring Garden St.	No tags
	Bus	10:00pm	1116 Woodruff Rd	15h	1:00pm	Philadelphia, 199 Spring Garden St	No tags

Next departures for Greenville to Philadelphia on December 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:50am	1116 Woodruff Rd	19h 55m	6:45am	199 Spring Garden St.	Cheapest
	Bus	10:00pm	1116 Woodruff Rd	13h 45m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
	Bus	7:25am	1116 Woodruff Rd	20h 20m	3:45am	199 Spring Garden St.	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	17h 5m	3:05pm	199 Spring Garden St.	No tags
	Bus	1:20pm	1116 Woodruff Rd	1d 1h	3:10pm	Cherry Hill Mall	No tags

Next departures for Greenville to Philadelphia on December 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:05pm	1116 Woodruff Rd	14h 10m	2:15am	Philadelphia, 199 Spring Garden St	Cheapest
	Bus	10:00pm	1116 Woodruff Rd	13h 45m	11:45am	Philadelphia, 199 Spring Garden St	Fastest
	Bus	7:25am	1116 Woodruff Rd	20h 20m	3:45am	199 Spring Garden St.	No tags
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	14h 30m	6:45am	199 Spring Garden St.	No tags
	Bus	4:15pm	1116 Woodruff Rd	16h 30m	8:45am	Philadelphia, 199 Spring Garden St	No tags

Last refresh of the prices: Today at 9:28 PM EST.

Compare 2 ways to go from Greenville to Philadelphia

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 16 hours 37 minutes and with fares starting at just $128, it presents an excellent value for a comfortable ride.

1train per day

16h 37mAverage Duration

530 milesDistance

78kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$76 - $334	Average Duration20h 15m	CO₂ emissions 21kg CO₂e
Train	Average Price$128 - $785	Average Duration16h 37m	CO₂ emissions 78kg CO₂e

Where are the popular stops in Greenville and Philadelphia?

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Stops in Philadelphia

A
Philadelphia Airport
Visit page
B
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
Visit page
C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA

Compare bus companies

FlixBus

3.5/511,524 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,415 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Greenville, SC to Philadelphia, PA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Greenville to Philadelphia?
The cheapest bus tickets from Greenville to Philadelphia start from $76. The average price for this route is around $127. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Philadelphia?
The average bus trip duration from Greenville to Philadelphia is 20h 15m, covering a distance of 526 miles (849 km). The quickest bus can get you there in 13h 45m and is operated by FlixBus.
Which bus companies service the Greenville to Philadelphia route?
Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Greenville to Philadelphia?
The earliest bus departs from Greenville to Philadelphia at 7:25am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Philadelphia?
A bus trip from Greenville to Philadelphia generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Greenville to Philadelphia?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Greenville to Philadelphia?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Greenville to Philadelphia?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Philadelphia?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/02

$149

12/03

$123

Today

$124

12/05

$119

12/06

$90

12/07

$105

12/08

$107

12/09

$93

The cheapest trip from Greenville, SC to Philadelphia, PA was searched and found on Dec 6, 2025 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Philadelphia, PA, as early as possible.

You can expect to pay from $90 to $187 for a bus ticket from Greenville, SC to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-12-06.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.