Bus from Harrisburg to Buffalo, NY: Tickets & Schedules

Next bus departures

Next departures for Harrisburg to Buffalo on January 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityCheapest
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityFastest
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityNo tags
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityNo tags

Last refresh of the prices: Yesterday at 6:53 PM EST.

Compare 2 ways to go from Harrisburg to Buffalo

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 14 hours 30 minutes and with fares starting at just $72, it presents an excellent value for a comfortable ride.

10bus per day
14h 30mAverage Duration
208 milesDistance
8kgCO₂ emissions
Average Price$72 - $263Average Duration14h 30m
8kg CO₂e
Average Price$112 - $354Average Duration13h 10m
30kg CO₂e

Frequently asked questions about traveling from Harrisburg to Buffalo, NY by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Harrisburg to Buffalo?

    The cheapest bus tickets from Harrisburg to Buffalo start from $72. The average price for this route is around $126. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Harrisburg to Buffalo?

    The average bus trip duration from Harrisburg to Buffalo is 14h 30m, covering a distance of 208 miles (335 km). The quickest bus can get you there in 13h 10m and is operated by Greyhound.

  3. Which bus companies service the Harrisburg to Buffalo route?

    Several major bus companies operate on this route with 10 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Harrisburg to Buffalo?

    The earliest bus departs from Harrisburg to Buffalo at 12:20am. And the latest bus departs at 11:20pm.

  5. What are the CO₂ emissions for the bus trip from Harrisburg to Buffalo?

    A bus trip from Harrisburg to Buffalo generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Harrisburg to Buffalo?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.

  7. Which bus company has the best Wi-Fi from Harrisburg to Buffalo?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Harrisburg to Buffalo?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Harrisburg to Buffalo?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/02
$97
01/03
$122
Today
$136
01/05
$111
01/06
$73
01/07
$82
01/08
$83
01/09
$80
busbud logoThe cheapest trip from Harrisburg to Buffalo, NY was searched and found on Jan 6, 2026 with a price of $73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Buffalo, NY, as early as possible.

You can expect to pay from $73 to $178 for a bus ticket from Harrisburg to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $73 which is on 2026-01-06.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Harrisburg to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

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