Compare 2 ways to go from Harrisburg to Winston-Salem.
Busbud recommends taking the train from Harrisburg to Winston-SalemAmong the sustainable travel choices, the train stands out as the good way to reach Winston-Salem. The journey takes about 14 hours 35 minutes and with fares starting at just $271, it presents an excellent value for a comfortable ride.
Bus Harrisburg to Winston-Salem: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Harrisburg to Winston-Salem Bus
Busbud helps you find a bus from Harrisburg to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Harrisburg to Winston-Salem will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Harrisburg to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Harrisburg and Winston-Salem?
Frequently asked questions for your trip Harrisburg - Winston-Salem
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Winston-Salem was searched and found on Jun 4, 2025 with a price of $72To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Winston-Salem, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Harrisburg and Winston-Salem!
Much more than a mere vehicle taking you from Harrisburg to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Harrisburg to Winston-Salem that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Harrisburg to Winston-Salem.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from Harrisburg to Winston-Salem?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.