Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | N. Houston Love's Travel Stop | Tupelo (Brothers Quick Stop) | No tags | ||||
 | Bus | Houston Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound | Bus | Downtown Gray & Smith | Tupelo (Brothers Quick Stop) | No tags | ||||
Greyhound + FlixBus | Bus | Houston Uptown/Upper Kirby | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Houston Bus Station | Tupelo (Brothers Quick Stop) | No tags |
Get from Houston to Tupelo
The journey takes about 23 hours 15 minutes and with fares starting at just THB 3,042, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Houston, US to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to Tupelo?
The cheapest bus tickets from Houston to Tupelo start from THB 3,042. The average price for this route is around THB 3,488. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to Tupelo?
The average bus trip duration from Houston to Tupelo is 23h 15m, covering a distance of 496 miles (800 km). The quickest bus can get you there in 20h 30m and is operated by Greyhound.
Which bus companies service the Houston to Tupelo route?
Several major bus companies operate on this route with 13 buses available per day.
What is the earliest and latest departure time for the bus from Houston to Tupelo?
The earliest bus departs from Houston to Tupelo at 12:05am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to Tupelo?
A bus trip from Houston to Tupelo generates an estimated 19.985625 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Tupelo was searched and found on Apr 23, 2026 with a price of THB 3,235To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Tupelo, as early as possible.
You can expect to pay from THB 3,235 to THB 3,912 for a bus ticket from Houston, US to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at THB 3,235 which is on 2026-04-23.
