Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Tupelo (Brothers Quick Stop) | Indianapolis Bus Station | No tags | |||||
Greyhound + FlixBus | Tupelo (Brothers Quick Stop) | Downtown Transit Center | No tags | |||||
| Tupelo (Brothers Quick Stop) | Indianapolis Bus Station | No tags | |||||
| Tupelo (Brothers Quick Stop) | Indianapolis Bus Station | No tags | |||||
Greyhound + FlixBus | Tupelo (Brothers Quick Stop) | Downtown Transit Center | No tags |
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Bus Tupelo to Indianapolis: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Tupelo to Indianapolis Bus
Busbud helps you find a bus from Tupelo to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Tupelo to Indianapolis.
Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Tupelo, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Tupelo - Indianapolis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Indianapolis was searched and found on Oct 4, 2025 with a price of $124To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Indianapolis, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tupelo and Indianapolis!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Tupelo to Indianapolis.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tupelo to Indianapolis.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tupelo to Indianapolis.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Tupelo
Buses Leaving from Tupelo
- Bus from Tupelo to Gainesville
- Bus Tupelo - Gainesville
- Tupelo - Milwaukee
- Bus from Tupelo to Memphis
- Bus Tupelo - Asheville
- Tupelo - Sacramento
- Bus from Tupelo to Atlanta
- Bus Tupelo - Orlando
- Tupelo - Nashville
- Bus from Tupelo to Chicago
- Bus Tupelo - Birmingham
- Tupelo - Austin
- Bus from Tupelo to Tampa
- Bus Tupelo - Jackson
- Tupelo - Toledo
Buses Going to Tupelo
- Bus from Nashville to Tupelo
- Bus Memphis - Tupelo
- Atlanta - Tupelo
- Bus from Biloxi to Tupelo
- Bus Chicago - Tupelo
- Jackson - Tupelo
- Bus from Orlando to Tupelo
- Bus Meridian - Tupelo
- Gary - Tupelo
- Bus from Houston to Tupelo
- Bus Birmingham - Tupelo
- St. Louis - Tupelo
- Bus from Tampa to Tupelo
- Bus Dallas - Tupelo
- Perry - Tupelo
Popular Buses Connecting Indianapolis
Buses Leaving from Indianapolis
- Bus from Indianapolis to Muncie
- Bus Indianapolis - Nashville
- Indianapolis - Chicago
- Bus from Indianapolis to Bloomington
- Bus Indianapolis - Bloomington
- Indianapolis - Temple
- Bus from Indianapolis to New York City
- Bus Indianapolis - Atlanta
- Indianapolis - Columbus
- Bus from Indianapolis to Cincinnati
- Bus Indianapolis - Boston
- Indianapolis - Orlando
- Bus from Indianapolis to Miami
- Bus Indianapolis - South Bend
- Indianapolis - Detroit
Buses Going to Indianapolis
- Bus from South Bend to Indianapolis
- Bus Bloomington - Indianapolis
- Bloomington - Indianapolis
- Bus from Merrillville to Indianapolis
- Bus Terre Haute - Indianapolis
- Greenfield - Indianapolis
- Bus from Chicago to Indianapolis
- Bus New York City - Indianapolis
- Columbus - Indianapolis
- Bus from Houston to Indianapolis
- Bus Detroit - Indianapolis
- Cincinnati - Indianapolis
- Bus from Atlanta to Indianapolis
- Bus Dallas - Indianapolis
- Nashville - Indianapolis
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Orlando - Atlanta
- Atlanta - Orlando