Bus Tickets from Jackson, MS, US to Indianapolis

Next departures

Next departures for Jackson to Indianapolis on November 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Jackson (Union Station)
    		Indianapolis Bus StationCheapest
    Greyhound Lines, Inc.
      		Jackson (Union Station)
      		Indianapolis Bus StationFastest
      Greyhound Lines, Inc.
        		Jackson (Union Station)
        		Indianapolis Bus StationNo tags
        Greyhound Lines, Inc. + FlixBus
          		Jackson (Union Station)
          		Downtown Transit CenterNo tags
          Greyhound Lines, Inc. + FlixBus
            		Jackson (Union Station)
            		Downtown Transit CenterNo tags

            Last refresh of the prices: Today at 1:00 PM CST.

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            Compare 2 ways to go from Jackson to Indianapolis

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 22 hours 5 minutes and with fares starting at just $120, it presents an excellent value for a comfortable ride.

            6bus per day
            22h 5mAverage Duration
            562 milesDistance
            23kgCO₂ emissions
            Bus
            		Average Price$120 - $331Average Duration22h 5m
            23kg CO₂e
            Train
            		Average Price$190 - $924Average Duration1d 5h
            82kg CO₂e

            Bus Jackson, MS, US to Indianapolis: Trip Overview

            Average ticket price$191
            Average bus trip duration22h 5m
            Number of daily buses6
            Earliest bus departure12:55pm
            Distance562 miles (905 km)
            Latest bus departure5:30pm

            Jackson to Indianapolis Bus

            With Busbud, comparing and booking tickets for a bus from Jackson to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            Bus service from Jackson to Indianapolis will be provided by the most trusted bus companies.

            From cheap bus tickets to more luxurious buses traveling from Jackson to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions for your trip Jackson, MS, US - Indianapolis

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/02
            No data
            11/03
            $166
            Today
            No data
            11/05
            $197
            11/06
            No data
            11/07
            No data
            11/08
            No data
            11/09
            No data
            busbud logoThe cheapest trip from Jackson, MS, US to Indianapolis was searched and found on Nov 3, 2025 with a price of $166

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jackson, MS, US to Indianapolis, as early as possible.

            You can expect to pay from $166 to $217 for a bus ticket from Jackson, MS, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $197 which is on 2025-11-05.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from Jackson to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Much more than a mere vehicle taking you from Jackson to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jackson to Indianapolis that are otherwise impossible to come by with a plane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Jackson to Indianapolis.

            Did you know?

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            What's the cheapest way to go from Jackson, MS, US to Indianapolis?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Jackson, MS, US by bus?

            Bus from Indianapolis to Jackson, MS, US

            You can also go to Indianapolis by train

            Train from Jackson, MS, US to Indianapolis

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