Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Jacksonville Bus Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Jacksonville Bus Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Jacksonville Bus Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Jacksonville Bus Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Jacksonville Bus Station | Opelika (4th Street Station) | No tags |
Get from Jacksonville to Opelika
The journey takes about 12 hours 15 minutes and with fares starting at just $86, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jacksonville and Opelika?
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Jacksonville, FL to Opelika by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Jacksonville to Opelika?
The cheapest bus tickets from Jacksonville to Opelika start from $86. The average price for this route is around $104. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Opelika?
The average bus trip duration from Jacksonville to Opelika is 12h 15m, covering a distance of 270 miles (435 km). The quickest bus can get you there in 13h 5m and is operated by Greyhound.
Which bus companies service the Jacksonville to Opelika route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Jacksonville to Opelika?
The earliest bus departs from Jacksonville to Opelika at 9:30am. And the latest bus departs at 9:25pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Opelika?
A bus trip from Jacksonville to Opelika generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Opelika was searched and found on Dec 26, 2025 with a price of $83To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Opelika, as early as possible.
You can expect to pay from $83 to $83 for a bus ticket from Jacksonville, FL to Opelika based on the last 2 days. You can expect to find the cheapest price for the trip at $83 which is on 2025-12-26.
