How much is the bus ticket from Karlsruhe to Palermo?

The cheapest bus tickets from Karlsruhe to Palermo start from $232. The average price for this route is around $232. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Karlsruhe to Palermo?

The average bus trip duration from Karlsruhe to Palermo is 1d 6h, covering a distance of 790 miles (1274 km). The quickest bus can get you there in 1d 6h and is operated by OneBus .

Which bus companies service the Karlsruhe to Palermo route?

Several major bus companies operate on this route with 1 buses available per day, including services from OneBus , FlixBus .

What is the earliest and latest departure time for the bus from Karlsruhe to Palermo?

The earliest bus departs from Karlsruhe to Palermo at 10:45am. And the latest bus departs at 10:45am.

What are the CO₂ emissions for the bus trip from Karlsruhe to Palermo?

A bus trip from Karlsruhe to Palermo generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Karlsruhe to Palermo?

According to Busbud customers, the highest-rated bus company on this route is OneBus , with an average rating of 4.0 out of 5 stars based on 14 reviews.

Which bus company has the best Wi-Fi from Karlsruhe to Palermo?

Based on reviews on Busbud, the bus company OneBus has the best Wi-Fi rating with a score of 5.0.

Which bus company has the most timely service from Karlsruhe to Palermo?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Karlsruhe to Palermo?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is OneBus , with a cleanliness rating of 4.4 out of 5 stars.

Bus Karlsruhe to Palermo from $109 | Refundable Tickets

Next departures

Next departures for Karlsruhe to Palermo on January 5
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:20am	Südseite Hauptbahnhof	1d 7h	11:00am	Terminal Bus Palermo	Cheapest
	7:50am	Südseite Hauptbahnhof	1d 6h	2:35pm	Palermo Centrale	Fastest
	3:50am	Südseite Hauptbahnhof	1d 10h	2:25pm	Terminal Bus Palermo	No tags
Flixtrain + Flixbus	3:29pm	Karlsruhe Hbf	1d 19h	11:00am	Terminal Bus Palermo	No tags
	11:40pm	Südseite Hauptbahnhof	1d 11h	11:00am	Terminal Bus Palermo	No tags

Last refresh of the prices: Last Tuesday at 5:13 PM CET.

Get from Karlsruhe to Palermo

This route is served by bus only

The journey takes about 1 day, 6 hours 45 minutes and with fares starting at just $232, it presents an excellent value for a comfortable ride.

1bus per day

1d 6hAverage Duration

790 milesDistance

32kgCO₂ emissions

Where are the popular stops in Karlsruhe and Palermo?

Stops in Karlsruhe

A
Südseite Hauptbahnhof
Hinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
Visit page
B
Karlsruhe Hbf
Bahnhofpl. 1A, 76137 Karlsruhe, Germany
Visit page
C
Goethestraße
Goethestraße 17-19, 76135 Karlsruhe, Germany
Visit page
D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany
E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany

Stops in Palermo

A
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy
Visit page
B
Palermo Airport
Punta Raisi, 90145, Palermo
Visit page
C
Piazza Cairoli
Piazza Cairoli, 8-14, 90123 Palermo, Italy
Visit page
D
Fiera
90143 Palermo PA, Italy
Visit page
E
Via Paolo Balsamo, 21
Via Paolo Balsamo, 21, 90123 Palermo, Italy
Visit page
F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy

Compare bus companies

OneBus

4/514 reviews

Staff4.5

Timeliness3.5

Cleanliness4.4

Wifi5

FlixBus

3.5/511,837 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Karlsruhe to Palermo by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Karlsruhe to Palermo?
The cheapest bus tickets from Karlsruhe to Palermo start from $232. The average price for this route is around $232. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Karlsruhe to Palermo?
The average bus trip duration from Karlsruhe to Palermo is 1d 6h, covering a distance of 790 miles (1274 km). The quickest bus can get you there in 1d 6h and is operated by OneBus.
Which bus companies service the Karlsruhe to Palermo route?
Several major bus companies operate on this route with 1 buses available per day, including services from OneBus, FlixBus.
What is the earliest and latest departure time for the bus from Karlsruhe to Palermo?
The earliest bus departs from Karlsruhe to Palermo at 10:45am. And the latest bus departs at 10:45am.
What are the CO₂ emissions for the bus trip from Karlsruhe to Palermo?
A bus trip from Karlsruhe to Palermo generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Karlsruhe to Palermo?
According to Busbud customers, the highest-rated bus company on this route is OneBus, with an average rating of 4.0 out of 5 stars based on 14 reviews.
Which bus company has the best Wi-Fi from Karlsruhe to Palermo?
Based on reviews on Busbud, the bus company OneBus has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from Karlsruhe to Palermo?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Karlsruhe to Palermo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is OneBus, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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The cheapest trip from Karlsruhe to Palermo was searched and found on Jan 5, 2026 with a price of $109

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Palermo, as early as possible.

You can expect to pay from $109 to $212 for a bus ticket from Karlsruhe to Palermo based on the last 0 days. You can expect to find the cheapest price for the trip at $109 which is on 2026-01-05.

Usually OneBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.