Is there a way to reach Winston-Salem from Knoxville without a car?

The best way to travel from Knoxville to Winston-Salem is by bus. Traveling by bus offers a budget-friendly, secure, and easy way to go between the two cities. Taking a ride with other travelers through carpool services is an additional option to consider.

How long is the bus ride from Knoxville to Winston-Salem?

On average, the trip from Knoxville to Winston-Salem takes around 11h 40m, but you can get there in as little as 11h 40m with the quickest bus. This is the time it takes to travel the 206 miles (332 km) that separate the two cities.

What is the distance between Knoxville and Winston-Salem?

The distance between the two cities is 206 miles (332 km).

What are the departure and arrival stations when taking the bus from Knoxville to Winston-Salem?

If you're headed to Winston-Salem from Knoxville, chances are that your bus will depart from 100 Kirkwood St and arrive at Winston Salem Greyhound Bus Station. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.

What is the cheapest way to get from Knoxville to Winston-Salem?

Go for the bus if you want the most cost-effective way to travel this route. $104 is the starting point for the cost-effective bus ride to Winston-Salem from Knoxville.

What is the ticket price for the bus trip from Knoxville to Winston-Salem?

The average bus ticket price from Knoxville to Winston-Salem is $123. Over the last 30 days, the prices ranged between $104 and $203, so make sure to compare them to get the best option.

Is it possible to travel by overnight bus from Knoxville to Winston-Salem?

Yes, it is possible to take an overnight bus from Knoxville to Winston-Salem. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.

Bus Knoxville (TN) to Winston-Salem from $83 | Compare & Save up to 10%

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from $90

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Cheap buses leaving Thursday

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: June 19 at 7:25pm
Departure city: Knoxville
Departure location: Knoxville Bus Station
Arrival time: June 20 at 7:00am
Destination city: Winston-Salem
Destination location: Winston Salem Greyhound Bus Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 11h 35m

Accepted payments

Bus Knoxville to Winston-Salem: Trip Overview

Average ticket price$123

Average bus trip duration11h 40m

Number of daily buses1

Earliest bus departure7:20pm

Distance203 miles (327 km)

Compare bus companies

Greyhound

3.5/587,034 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Knoxville to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from Knoxville to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Winston-Salem.

Whether it is cheap bus tickets or more luxurious buses going to Winston-Salem from Knoxville, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Knoxville and Winston-Salem?

Stops in Knoxville

A - 100 Kirkwood St

Stops in Winston-Salem

A - Winston Salem Greyhound Bus Station

B - E Sprague St

C - Winston-Salem Bus Stop

D - 1237 Silas Creek Pkwy

Frequently asked questions for your trip Knoxville (TN) - Winston-Salem

Is there a way to reach Winston-Salem from Knoxville without a car?
How long is the bus ride from Knoxville to Winston-Salem?
What is the distance between Knoxville and Winston-Salem?
What are the departure and arrival stations when taking the bus from Knoxville to Winston-Salem?
What is the cheapest way to get from Knoxville to Winston-Salem?
What is the ticket price for the bus trip from Knoxville to Winston-Salem?
Is it possible to travel by overnight bus from Knoxville to Winston-Salem?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

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06/19

$83

The cheapest trip from Knoxville to Winston-Salem was searched and found on Jun 19, 2025 with a price of $83

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Winston-Salem, as early as possible.

You can expect to pay from $83 to $83 for a bus ticket from Knoxville to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $83 which is on 2025-06-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Knoxville to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Winston-Salem.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Winston-Salem.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Winston-Salem.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Knoxville by bus?

Bus from Knoxville to Winston-Salem

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Knoxville (TN) to Winston-Salem

Cheap buses leaving Thursday

One passenger / one way

Bus Knoxville to Winston-Salem: Trip Overview

Compare bus companies

Knoxville to Winston-Salem Bus

Where are the popular stops in Knoxville and Winston-Salem?

Frequently asked questions for your trip Knoxville (TN) - Winston-Salem

Is there a way to reach Winston-Salem from Knoxville without a car?

How long is the bus ride from Knoxville to Winston-Salem?

What is the distance between Knoxville and Winston-Salem?

What are the departure and arrival stations when taking the bus from Knoxville to Winston-Salem?

What is the cheapest way to get from Knoxville to Winston-Salem?

What is the ticket price for the bus trip from Knoxville to Winston-Salem?

Is it possible to travel by overnight bus from Knoxville to Winston-Salem?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Knoxville by bus?

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

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