Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | La Crosse (U of WI) | Sioux Falls | No tags | ||||
| Bus | 314 Jay St., La Crosse | Sioux Falls | No tags |
Get from La Crosse to Sioux Falls
The journey takes about 20 hours 55 minutes and with fares starting at just $184, it presents an excellent value for a comfortable ride.
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Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Frequently asked questions about traveling from La Crosse, WI to Sioux Falls by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from La Crosse to Sioux Falls?
The cheapest bus tickets from La Crosse to Sioux Falls start from $184. The average price for this route is around $184. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from La Crosse to Sioux Falls?
The average bus trip duration from La Crosse to Sioux Falls is 20h 55m, covering a distance of 278 miles (447 km). The quickest bus can get you there in 20h 55m and is operated by Jefferson Lines.
Which bus companies service the La Crosse to Sioux Falls route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from La Crosse to Sioux Falls?
The earliest bus departs from La Crosse to Sioux Falls at 12:25pm. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from La Crosse to Sioux Falls?
A bus trip from La Crosse to Sioux Falls generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
