Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lafayette Bus Stop | Mesa Bus Stop | No tags | ||||
Greyhound + FlixBus | Bus | Lafayette Bus Stop | Mesa Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | Lafayette Bus Stop | Mesa Bus Stop | No tags |
Get from Lafayette to Mesa
The journey takes about 2 days, 1 hour 20 minutes and with fares starting at just $225, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lafayette and Mesa?
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Lafayette, IN to Mesa by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lafayette to Mesa?
The cheapest bus tickets from Lafayette to Mesa start from $225. The average price for this route is around $225. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lafayette to Mesa?
The average bus trip duration from Lafayette to Mesa is 2d 1h, covering a distance of 1453 miles (2343 km). The quickest bus can get you there in 1d 17h and is operated by Greyhound.
Which bus companies service the Lafayette to Mesa route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Lafayette to Mesa?
The earliest bus departs from Lafayette to Mesa at 5:00pm. And the latest bus departs at 9:45pm.
What are the CO₂ emissions for the bus trip from Lafayette to Mesa?
A bus trip from Lafayette to Mesa generates an estimated 59 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lafayette, IN to Mesa was searched and found on Jan 17, 2026 with a price of $218To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, IN to Mesa, as early as possible.
You can expect to pay from $218 to $218 for a bus ticket from Lafayette, IN to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at $218 which is on 2026-01-17.
