Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Exit 122 Park & Ride | Buffalo (BUF) Airport | CheapestFastest | ||||
| Bus | Exit 122 Park & Ride | Buffalo (BUF) Airport | No tags | ||||
| Bus | Exit 122 Park & Ride | Transportation Center | No tags | ||||
| Bus | Exit 122 Park & Ride | Transportation Center | No tags |
Last refresh of the prices: Last Sunday at 6:59 PM EDT.
Get from Middletown to Buffalo
The journey takes about 11 hours 15 minutes and with fares starting at just CHF 117, it presents an excellent value for a comfortable ride.
Bus stations and stops in Middletown and Buffalo
Stops in Buffalo
- B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA - C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Based on 1165 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the cleanliness but often complained with the wifi. Adirondack Trailways ticket prices on this trip start at CHF 117
Frequently asked questions about traveling from Middletown, NY, US to Buffalo, NY by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Middletown to Buffalo?
The cheapest bus tickets from Middletown to Buffalo start from CHF 117. The average price for this route is around CHF 123. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Middletown to Buffalo?
The average bus trip duration from Middletown to Buffalo is 11h 15m, covering a distance of 249 miles (401 km). The quickest bus can get you there in 10h 45m and is operated by Adirondack Trailways.
Which bus companies service the Middletown to Buffalo route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Middletown to Buffalo?
The earliest bus departs from Middletown to Buffalo at 9:55am. And the latest bus departs at 5:00pm.
What are the CO₂ emissions for the bus trip from Middletown to Buffalo?
A bus trip from Middletown to Buffalo generates an estimated 10.012475 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Middletown, NY, US to Buffalo, NY was searched and found on Jul 13, 2026 with a price of CHF 109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Middletown, NY, US to Buffalo, NY, as early as possible.
You can expect to pay from CHF 109 to CHF 115 for a bus ticket from Middletown, NY, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 114 which is on 2026-07-19.
