Bus Tickets from Milan to Karlsruhe

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TodayMay 10
from $50
TomorrowMay 11
from $39
MonMay 12
TueMay 13
WedMay 14
ThuMay 15
FriMay 16
SatMay 17

Next departures to Karlsruhe

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 11 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 11 at
    Destination city: Karlsruhe
    Destination location: Südseite Hauptbahnhof
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 11 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 12 at
    Destination city: Karlsruhe
    Destination location: Südseite Hauptbahnhof
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 11 at
    Destination city: Karlsruhe
    Destination location: Südseite Hauptbahnhof
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 12 at
    Destination city: Karlsruhe
    Destination location: Karlsruhe Hbf
    Operated by: Flixbus + Flixtrain
    Flixbus + Flixtrain
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 11 at
    Destination city: Karlsruhe
    Destination location: Südseite Hauptbahnhof
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to go from Milan to Karlsruhe.

Bus
Average Price$30 - $225Average Duration9h 40m
9kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$44 - $50Average Duration6h 20m
17kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milan to Karlsruhe

Among the sustainable travel choices, the carpool stands out as the good way to reach Karlsruhe. The journey takes about 6 hours 20 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.

1carpool per day
6h 20mAverage Duration
$44Cheapest ticket
17kgCO₂ emissions

Bus Milan to Karlsruhe: Trip Overview

Average ticket price$63
Average bus trip duration9h 40m
Number of daily buses2
Earliest bus departure1:00am
Distance233 miles (375 km)
Latest bus departure11:45pm

Milan to Karlsruhe Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Milan to Karlsruhe.

We make sure you can find a bus service from Milan to Karlsruhe from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Milan to Karlsruhe, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Milan - Karlsruhe

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/08
No data
05/09
$51
Today
$50
05/11
$39
05/12
$35
05/13
No data
05/14
$69
05/15
No data
busbud logoThe cheapest trip from Milan to Karlsruhe was searched and found on May 12, 2025 with a price of $35

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milan to Karlsruhe, as early as possible.

You can expect to pay from $35 to $111 for a bus ticket from Milan to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-05-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Milan to Karlsruhe but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milan to Karlsruhe, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Milan to Karlsruhe that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milan to Karlsruhe.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Milan by bus?

Bus from Milan to Karlsruhe

You can also go to Karlsruhe by train

Train from Milan to Karlsruhe

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