Next departures for Milano to Karlsruhe on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lampugnano
Karlsruhe
Cheapest
Bus
Lampugnano
Karlsruhe
Fastest
Next departures for Milano to Karlsruhe on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lampugnano
Karlsruhe
CheapestFastest
Bus
Lampugnano
Karlsruhe
No tags
Next departures for Milano to Karlsruhe on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lampugnano
Karlsruhe
Cheapest
Bus
Milan Via Giuseppe Impastato
Südseite Hauptbahnhof
Fastest
Last refresh of the prices: Yesterday at 2:51 PM CET.
Compare 2 ways to go from Milano to Karlsruhe
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Karlsruhe. The journey takes about 5 hours 50 minutes and with fares starting at just $32, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11145 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $35
Based on 894 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the staff and the temperature but often complained with the wifi. MarinoBus ticket prices on this trip start at $58
Frequently asked questions about traveling from Milano to Karlsruhe by bus
How far is Milano from Karlsruhe?
Milano and Karlsruhe are 248 miles (399 km) apart.
What are the departure and arrival stations when taking the bus from Milano to Karlsruhe?
Most of the buses traveling from Milano to Karlsruhe leave from Piazza I Maggio, 1 and arrive at Südseite Hauptbahnhof. These are the primary departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Karlsruhe?
Once in Karlsruhe, you can start exploring the city and discover its surroundings. The top sights and things to do are Weinstube im Baldreit (Baden-Baden), Hoepfner Burghof (Karlsruhe), Leo's Baden-Baden, Restaurant EigenArt (Karlsruhe) and La Casserole (Baden-Baden).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
No data
11/21
$87
Today
$51
11/23
$83
11/24
No data
11/25
No data
11/26
$56
11/27
$43
The cheapest trip from Milano to Karlsruhe was searched and found on Nov 27, 2025 with a price of $43
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Karlsruhe, as early as possible.
You can expect to pay from $43 to $137 for a bus ticket from Milano to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $43 which is on 2025-11-27.
Usually MarinoBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Milano to Karlsruhe was searched and found on Nov 27, 2025 with a price of $43
