Next bus departures
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Last refresh of the prices: Today at 12:33 AM EDT.
Get from Myrtle Beach to Florence
The journey takes about 1 hour 40 minutes and with fares starting at just $19, it presents an excellent value for a comfortable ride.
Bus stations and stops in Myrtle Beach and Florence
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Myrtle Beach to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Myrtle Beach to Florence?
The cheapest bus tickets from Myrtle Beach to Florence start from $19. The average price for this route is around $22. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Myrtle Beach to Florence?
The average bus trip duration from Myrtle Beach to Florence is 1h 40m, covering a distance of 61 miles (99 km). The quickest bus can get you there in 1h 20m and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Florence route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Florence?
The earliest bus departs from Myrtle Beach to Florence at 11:50am. And the latest bus departs at 5:05pm.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Florence?
A bus trip from Myrtle Beach to Florence generates an estimated 2.4557749999999996 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Florence, SC, US was searched and found on Oct 15, 2026 with a price of $12To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Florence, SC, US, as early as possible.
You can expect to pay from $12 to $32 for a bus ticket from Myrtle Beach to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $12 which is on 2026-10-19.
