What is the distance between Baltimore and Florence?

The distance separating Baltimore and Florence is 389 miles (627 km).

What are the departure and arrival stations when taking the bus from Baltimore to Florence?

If you're headed to Florence from Baltimore, chances are that your bus will leave from Baltimore Downtown Bus Station and arrive at Florence Bus Station. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Museo Galileo - Institute and Museum of the History of Science, Galleria degli Uffizi, Villa Gamberaia, Basilica Santa Croce and Galleria dell’Accademia.

Bus Baltimore to Florence from $68 | Compare & Save up to 40%

TodayJul 31

from $81

TomorrowAug 1

from $110

SatAug 2

from $79

SunAug 3

from $75

MonAug 4

TueAug 5

from $62

WedAug 6

from $63

ThuAug 7

from $67

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: August 1 at 11:10pm
Departure city: Baltimore
Departure location: O'Donnell St. & Travel Plaza, Infront of TA Gas station
Arrival time: August 2 at 8:00am
Destination city: Florence
Destination location: 2301 W Lucas St.
Operated by: Wanda Coach
Vehicle: BusDuration: 8h 50m
Departure time: August 1 at 2:05am
Departure city: Baltimore
Departure location: Baltimore Downtown Bus Station
Arrival time: August 1 at 12:45pm
Destination city: Florence
Destination location: Bus station
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 10h 40m
Departure time: August 1 at 8:30pm
Departure city: Baltimore
Departure location: Baltimore Downtown Bus Station
Arrival time: August 2 at 5:45am
Destination city: Florence
Destination location: Florence, SC
Operated by: FlixBus
Vehicle: BusDuration: 9h 15m
Departure time: August 1 at 11:25pm
Departure city: Baltimore
Departure location: Baltimore Downtown Bus Station
Arrival time: August 2 at 12:45pm
Destination city: Florence
Destination location: Bus station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 13h 20m
Departure time: August 1 at 2:50pm
Departure city: Baltimore
Departure location: Baltimore Bus Stop
Arrival time: August 2 at 5:45am
Destination city: Florence
Destination location: Florence, SC
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 14h 55m

Accepted payments

Compare 2 ways to go from Baltimore to Florence.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$58 - $195	Average Duration10h 40m	CO₂ emissions 16kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$83 - $312	Average Duration9h 12m	CO₂ emissions 58kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Baltimore to Florence

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 9 hours 12 minutes and with fares starting at just $83, it presents an excellent value for a comfortable ride.

3train per day

9h 12mAverage Duration

$83Cheapest ticket

58kgCO₂ emissions

Bus Baltimore to Florence, SC, US: Trip Overview

Average ticket price$97

Average bus trip duration10h 40m

Number of daily buses5

Earliest bus departure2:05am

Distance391 miles (630 km)

Latest bus departure11:25pm

Compare bus companies

FlixBus

3.5/59,823 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Wanda Coach

2.5/5617 reviews

Staff3

Timeliness2.8

Cleanliness2.4

Wifi1.7

Wanda Coach is one of the main Chinatown bus carriers in the US, connecting about 75 cities around the country with inexpensive tickets and comfortable bus rides. Wanda Coach buses travel between Chinatown neighborhoods with direct buses that are affordable, safe and have convenient pick-up and drop-off locations. If you travel with Wanda Coach, you can reschedule your tickets for a $10 fee up to 2 hours before travel time, and their buses have free WiFi, power outlets and bathrooms.

Greyhound

3.5/587,147 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Tufesa, Valley Transit, Wanda Coach

Baltimore to Florence Bus

Busbud helps you find a bus from Baltimore to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Baltimore to Florence will be provided by the most trusted bus companies.

Discover how much the bus trip from Baltimore to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Baltimore and Florence?

Stops in Baltimore

A - Baltimore Downtown Bus Station

B - Penn Station

C - Baltimore Airport

D - Maryland Ave & I-83

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions for your trip Baltimore - Florence, SC, US

What is the distance between Baltimore and Florence?
What are the departure and arrival stations when taking the bus from Baltimore to Florence?
What are the best sights and things to do in Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07/29

$98

07/30

$100

Today

$87

08/01

$100

08/02

$100

08/03

$89

08/04

$74

08/05

$100

The cheapest trip from Baltimore to Florence, SC, US was searched and found on Aug 4, 2025 with a price of $74

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, SC, US, as early as possible.

You can expect to pay from $74 to $117 for a bus ticket from Baltimore to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-08-04.

Usually FlixBus Inc., iLIKEBUS will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Baltimore and Florence!

Much more than a mere vehicle taking you from Baltimore to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Baltimore to Florence will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Baltimore to Florence.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Baltimore to Florence, SC, US?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time10h 40m	Avg Price$97	Daily Departures5
Vehicle TypeTrain	Travel Time9h 12m	Avg Price$124	Daily Departures3

Will you be returning to Baltimore by bus?

Bus from Baltimore to Florence, SC, US

You can also go to Florence, SC, US by train

Train from Baltimore to Florence, SC, US

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Baltimore to Florence, SC, US

One passenger / one way

Cheap buses leaving tomorrow

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from Baltimore to Florence.

Bus Baltimore to Florence, SC, US: Trip Overview

Compare bus companies

Baltimore to Florence Bus

Where are the popular stops in Baltimore and Florence?

Frequently asked questions for your trip Baltimore - Florence, SC, US

What is the distance between Baltimore and Florence?

What are the departure and arrival stations when taking the bus from Baltimore to Florence?

What are the best sights and things to do in Florence?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Baltimore to Florence, SC, US?

Will you be returning to Baltimore by bus?

You can also go to Florence, SC, US by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular bus departures from Baltimore

Popular bus departures to Baltimore

Continue your journey from Florence