Bus Tickets from New York City to Florence, SC, US

Next departures

Next departures for New York City to Florence on August 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
NYC Midtown (31st St & 8th Ave)
Bus stationCheapest
Wanda Coach
95 Canal St
2301 W Lucas St.Fastest
Wanda Coach
95 Canal St
2301 W Lucas St.No tags
Greyhound Lines, Inc. + FlixBus
New York Port Authority
Bus stationNo tags
FlixBus
NYC Midtown (31st St & 8th Ave)
Florence, SCNo tags

Accepted payments

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Compare 2 ways to go from New York City to Florence.

Average Price$69 - $269Average Duration14h 45m
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$100 - $349Average Duration11h 52m
81kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from New York City to Florence

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 11 hours 52 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.

2train per day
11h 52mAverage Duration
$100Cheapest ticket
81kgCO₂ emissions

Bus New York City to Florence, SC, US: Trip Overview

Average ticket price$127
Average bus trip duration14h 45m
Number of daily buses18
Earliest bus departure10:15am
Distance552 miles (889 km)
Latest bus departure11:00pm

New York City to Florence Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from New York City to Florence.

We make sure you can find a bus service from New York City to Florence from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Florence from New York City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip New York City - Florence, SC, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/23
$120
08/24
$120
Today
$103
08/26
$120
08/27
$100
08/28
$120
08/29
$120
08/30
$120
busbud logoThe cheapest trip from New York City to Florence, SC, US was searched and found on Aug 27, 2025 with a price of $100

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to Florence, SC, US, as early as possible.

You can expect to pay from $100 to $223 for a bus ticket from New York City to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $100 which is on 2025-08-27.

Usually Wanda Coach, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from New York City to Florence but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New York City to Florence, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from New York City to Florence.

Tune out to the fine sounds of your best music playlist on your bus trip from New York City to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from New York City to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to New York City by bus?

Bus from Florence, SC, US to New York City

You can also go to Florence, SC, US by train

Train from New York City to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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