Bus Tickets from New York City to Florence, SC, US
Next bus departures
Next departures for New York City to Florence on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
95 Canal St
2301 W Lucas St.
CheapestFastest
Bus
103 Canal St
2301 W Lucas St.
No tags
Bus
New York Port Authority
Bus station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
Florence, SC
No tags
Bus
NYC Midtown (31st St & 8th Ave)
Florence, SC
No tags
Next departures for New York City to Florence on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
95 Canal St
2301 W Lucas St.
CheapestFastest
Bus
103 Canal St
2301 W Lucas St.
No tags
Bus
New York Port Authority
Bus station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New York Port Authority
Florence, SC
No tags
Bus
NYC Midtown (31st St & 8th Ave)
Florence, SC
No tags
Last refresh of the prices: Yesterday at 11:03 PM EST.
Compare 2 ways to go from New York City to Florence
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 11 hours 53 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Wanda Coach is one of the main Chinatown bus carriers in the US, connecting about 75 cities around the country with inexpensive tickets and comfortable bus rides. Wanda Coach buses travel between Chinatown neighborhoods with direct buses that are affordable, safe and have convenient pick-up and drop-off locations. If you travel with Wanda Coach, you can reschedule your tickets for a $10 fee up to 2 hours before travel time, and their buses have free WiFi, power outlets and bathrooms.
Wanda Coach New York City Florence recent customer reviews
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.
Frequently asked questions about traveling from New York City to Florence, SC, US by bus
What is the travel distance from New York City to Florence?
The distance separating New York City and Florence is 545 miles (879 km).
What are the departure and arrival stations when taking the bus from New York City to Florence?
The majority of buses traveling from New York City to Florence start their journey at GW Bridge and wind up at Florence Bus Station. These are the most popular pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Florence?
Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Galleria degli Uffizi, Palazzo Vecchio, Palazzo Pitti, Museo degli Innocenti and Cooking Classes in Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/22
$120
11/23
$120
Today
$120
11/25
$120
11/26
$120
11/27
$108
11/28
$120
11/29
$120
The cheapest trip from New York City to Florence, SC, US was searched and found on Nov 27, 2025 with a price of $108
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to Florence, SC, US, as early as possible.
You can expect to pay from $108 to $296 for a bus ticket from New York City to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $108 which is on 2025-11-27.
Usually FlixBus, Wanda Coach, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from New York City to Florence, SC, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from New York City to Florence, SC, US was searched and found on Nov 27, 2025 with a price of $108
The bus is the cheapest travel choice for this destination
