- Portland to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Portland Curbside Bus Stop | Knoxville Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Portland Curbside Bus Stop | Knoxville Bus Station | No tags | ||||
![]() | Bus | Portland Curbside Bus Stop | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Portland Curbside Bus Stop | Knoxville Bus Station | No tags | ||||
![]() | Bus | Portland Curbside Bus Stop | Knoxville Bus Station | No tags |
Get from Portland to Knoxville
The journey takes about 2 days, 23 hours 50 minutes and with fares starting at just $286, it presents an excellent value for a comfortable ride.
Where are the popular stops in Portland and Knoxville?
Stops in Portland
- B7411 Northwest Station Way, Portland OR 97209, USA
- C
NW Everett & NW 8th Ave
728 NW Everett St, Portland, OR 97209, USA - D
Lloyd Center
NE 13th Ave & Holladay, Portland, OR 97232, USA - E
Pearl District
7418 NW Station Way (across street), Portland, OR 97209, USA
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Portland, OR to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Portland to Knoxville?
The cheapest bus tickets from Portland to Knoxville start from $286. The average price for this route is around $321. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Portland to Knoxville?
The average bus trip duration from Portland to Knoxville is 2d 23h, covering a distance of 2107 miles (3398 km). The quickest bus can get you there in 3d 13h and is operated by Greyhound.
Which bus companies service the Portland to Knoxville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Portland to Knoxville?
The earliest bus departs from Portland to Knoxville at 7:50pm. And the latest bus departs at 7:50pm.
What are the CO₂ emissions for the bus trip from Portland to Knoxville?
A bus trip from Portland to Knoxville generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






