- San Antonio to Key West buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Pearl District | Key West Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | San Antonio Bus Station | Caroline St | No tags | ||||
FlixBus + Greyhound | Bus | San Antonio Bus Station | Caroline St | No tags | ||||
![]() | Bus | San Antonio Bus Station | Key West Bus Station | No tags | ||||
Valley Transit + Greyhound | Bus | San Antonio Bus Station | Key West Bus Station | No tags |
Get from San Antonio to Key West
The journey takes about 1 day, 19 hours and with fares starting at just $225, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Antonio and Key West?
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from San Antonio, US to Key West by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Antonio to Key West?
The cheapest bus tickets from San Antonio to Key West start from $225. The average price for this route is around $225. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to Key West?
The average bus trip duration from San Antonio to Key West is 1d 19h, covering a distance of 1081 miles (1743 km). The quickest bus can get you there in 1d 19h and is operated by Greyhound.
Which bus companies service the San Antonio to Key West route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from San Antonio to Key West?
The earliest bus departs from San Antonio to Key West at 1:30pm. And the latest bus departs at 1:30pm.
What are the CO₂ emissions for the bus trip from San Antonio to Key West?
A bus trip from San Antonio to Key West generates an estimated 44 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






