Bus Tickets from San Diego, CA, US to Syracuse, US

Find affordable bus tickets from San Diego, CA, US to Syracuse, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 29
TomorrowJun 30
TueJul 1
WedJul 2
ThuJul 3
from $286
FriJul 4
SatJul 5
SunJul 6

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 3 at
    Departure city: San Diego
    Departure location: 5716 Hardy Ave
    Arrival time: July 6 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 3 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: July 6 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 3 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: July 6 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 3 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: July 6 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 3 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: July 6 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Diego to Syracuse.

Bus
Average Price$286 - $316Average Duration2d 23h
93kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$406 - $639Average Duration2d 18h
340kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from San Diego to Syracuse

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 2 days, 23 hours 10 minutes and with fares starting at just $286, it presents an excellent value for a comfortable ride.

7bus per day
2d 23hAverage Duration
$286Cheapest ticket
93kgCO₂ emissions

Bus San Diego to Syracuse: Trip Overview

Average ticket price$290
Average bus trip duration2d 23h
Number of daily buses7
Earliest bus departure9:00am
Distance2317 miles (3736 km)
Latest bus departure7:35pm

San Diego to Syracuse Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Diego to Syracuse.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Syracuse.

From cheap bus tickets to more luxurious buses traveling from San Diego to Syracuse, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Diego, CA, US - Syracuse, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/27
No data
06/28
No data
Today
No data
06/30
No data
07/01
No data
07/02
No data
07/03
$279
07/04
No data
busbud logoThe cheapest trip from San Diego to Syracuse was searched and found on Jul 3, 2025 with a price of $279

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Syracuse, as early as possible.

You can expect to pay from $279 to $279 for a bus ticket from San Diego to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $279 which is on 2025-07-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Diego to Syracuse but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Diego to Syracuse.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Syracuse that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Syracuse while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from San Diego to Syracuse?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego by bus?

Bus from San Diego to Syracuse

You can also go to Syracuse by train

Train from San Diego to Syracuse

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego

Popular Buses Connecting Syracuse

Buses Leaving from Syracuse

Buses Going to Syracuse