Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Sur | Penco | No tags | ||||
| Bus | Terminal Sur | Penco | No tags | ||||
| Bus | Terminal Sur | Penco | No tags | ||||
| Bus | Terminal Sur | Penco | No tags | ||||
| Bus | Terminal Sur | Penco | No tags |
Get from Santiago to Penco
The journey takes about 5 hours 6 minutes and with fares starting at just $14, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago and Penco?
Stops in Santiago
- ATucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- BSantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- C
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Stops in Penco
- A
Terminal de Autobuses de Penco
Ruta 150 9, Penco, Región del Bío Bío, Chile
Compare bus companies
Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the wifi. Eme Bus ticket prices on this trip start at $14
Frequently asked questions about traveling from Santiago, CL to Penco by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santiago to Penco?
The cheapest bus tickets from Santiago to Penco start from $14. The average price for this route is around $20. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santiago to Penco?
The average bus trip duration from Santiago to Penco is 5h 6m, covering a distance of 261 miles (421 km). The quickest bus can get you there in 5h 5m and is operated by Eme Bus.
Which bus companies service the Santiago to Penco route?
Several major train operators operate on this route with 10 trains available per day.
What is the earliest and latest departure time for the bus from Santiago to Penco?
The earliest bus departs from Santiago to Penco at 12:30am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Santiago to Penco?
A bus trip from Santiago to Penco generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to Penco was searched and found on Nov 27, 2025 with a price of $13To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Penco, as early as possible.
