Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Sur | Parada Pueblo Seco | CheapestFastest | ||||
| Bus | Terminal Sur | Parada Pueblo Seco | No tags |
Last refresh of the prices: Today at 2:34 PM -03.
Get from Santiago to Pueblo Seco
The journey takes about 5 hours 30 minutes and with fares starting at just $18, it presents an excellent value for a comfortable ride.
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Frequently asked questions about traveling from Santiago, CL to Pueblo Seco by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santiago to Pueblo Seco?
The cheapest bus tickets from Santiago to Pueblo Seco start from $18. The average price for this route is around $21. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santiago to Pueblo Seco?
The average bus trip duration from Santiago to Pueblo Seco is 5h 30m, covering a distance of 250 miles (402 km). The quickest bus can get you there in 5h 2m and is operated by Buses Jet Sur.
Which bus companies service the Santiago to Pueblo Seco route?
Several major bus companies operate on this route with 2 buses available per day, including services from buses TranSantin, Buses Jet Sur.
What is the earliest and latest departure time for the bus from Santiago to Pueblo Seco?
The earliest bus departs from Santiago to Pueblo Seco at 1:15pm. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Santiago to Pueblo Seco?
A bus trip from Santiago to Pueblo Seco generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santiago to Pueblo Seco?
According to Busbud customers, the highest-rated bus company on this route is buses TranSantin, with an average rating of 4.2 out of 5 stars based on 280 reviews.
Which bus company has the best Wi-Fi from Santiago to Pueblo Seco?
Based on reviews on Busbud, the bus company buses TranSantin has the best Wi-Fi rating with a score of 1.7.
Which bus company has the most timely service from Santiago to Pueblo Seco?
According to Busbud traveller reviews, the most timely bus company on this route is Buses Jet Sur, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santiago to Pueblo Seco?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is buses TranSantin, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to Pueblo Seco was searched and found on Nov 26, 2025 with a price of $15To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Pueblo Seco, as early as possible.
You can expect to pay from $15 to $30 for a bus ticket from Santiago, CL to Pueblo Seco based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2025-11-28.
