Next departures for St. Louis to Cincinnati on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Cincinnati Bus Station
CheapestFastest
Bus
Gateway Station
Cincinnati Bus Station
No tags
Next departures for St. Louis to Cincinnati on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Cincinnati Bus Station
Cheapest
Bus
Gateway Station
Cincinnati Bus Station
Fastest
Next departures for St. Louis to Cincinnati on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Cincinnati Bus Station
CheapestFastest
Bus
Gateway Station
Cincinnati Bus Station
No tags
Last refresh of the prices: Today at 7:55 AM CST.
Compare 2 ways to go from St. Louis to Cincinnati
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Cincinnati. The journey takes about 6 hours 50 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound St. Louis Cincinnati recent customer reviews
My original bus showed up 40 minutes late, so when I arrived to my transfer station the next bus had already left and I spent 8 more hours on buses than I should have.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from St. Louis to Cincinnati by bus
What is the distance between St. Louis and Cincinnati?
The distance separating St. Louis and Cincinnati is 311 miles (501 km).
What are the departure and arrival stations when taking the bus from St. Louis to Cincinnati?
If you're headed to Cincinnati from St. Louis, chances are that your bus will leave from Gateway Station and arrive at Greyhound Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$100
11/22
$91
Today
$90
11/24
$83
11/25
$66
11/26
$64
11/27
$55
11/28
No data
The cheapest trip from St. Louis to Cincinnati was searched and found on Nov 27, 2025 with a price of $55
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Cincinnati, as early as possible.
You can expect to pay from $55 to $140 for a bus ticket from St. Louis to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-27.
What's the cheapest way to go from St. Louis to Cincinnati?
The bus is the cheapest travel choice for this destination