Bus Tickets from Syracuse, US to Charlotte, NC

Next departures

Next departures for Syracuse to Charlotte on October 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Charlotte Bus StationCheapestFastest
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Charlotte Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Charlotte (Freedom Dr)No tags
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Charlotte Bus StationNo tags
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Charlotte Bus StationNo tags

Last refresh of the prices: Today at 5:43 PM EDT.

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Compare 2 ways to go from Syracuse to Charlotte

Bus
Average Price$75 - $359Average Duration20h 35m
24kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$190 - $1,038Average Duration19h 26m
87kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Syracuse to Charlotte

Among the sustainable travel choices, the train stands out as the good way to reach Charlotte. The journey takes about 19 hours 26 minutes and with fares starting at just $190, it presents an excellent value for a comfortable ride.

1train per day
19h 26mAverage Duration
$190Cheapest ticket
87kgCO₂ emissions

Bus Syracuse, US to Charlotte, NC: Trip Overview

Average ticket price$152
Average bus trip duration20h 35m
Number of daily buses9
Earliest bus departure1:15am
Distance596 miles (961 km)
Latest bus departure9:00pm

Syracuse to Charlotte Bus

Busbud helps you find a bus from Syracuse to Charlotte. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Syracuse to Charlotte.

Discover how much the bus trip from Syracuse to Charlotte will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Syracuse, US - Charlotte, NC

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/19
$152
10/20
$125
Today
$127
10/22
$129
10/23
$97
10/24
$97
10/25
$95
10/26
$91
busbud logoThe cheapest trip from Syracuse, US to Charlotte, NC was searched and found on Oct 26, 2025 with a price of $91

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Charlotte, NC, as early as possible.

You can expect to pay from $91 to $279 for a bus ticket from Syracuse, US to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-10-26.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Syracuse and Charlotte!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Syracuse to Charlotte.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Syracuse to Charlotte will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Syracuse to Charlotte while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Syracuse, US to Charlotte, NC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse, US by bus?

Bus from Charlotte, NC to Syracuse, US

You can also go to Charlotte, NC by train

Train from Syracuse, US to Charlotte, NC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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