Next departures for Syracuse to Boston on November 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Brookline
Fastest
Next departures for Syracuse to Boston on November 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
CheapestFastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
New York Trailways + Peter Pan
Bus
Amtrak Station
Boston (South Station)
No tags
Next departures for Syracuse to Boston on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
Cheapest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
Fastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Next departures for Syracuse to Boston on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
CheapestFastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
New York Trailways + Peter Pan
Bus
Amtrak Station
Boston (South Station)
No tags
Next departures for Syracuse to Boston on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
CheapestFastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
New York Trailways + Peter Pan
Bus
Amtrak Station
Boston (South Station)
No tags
Next departures for Syracuse to Boston on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Adirondack Trailways + Peter Pan
Bus
Amtrak Station
Boston (South Station)
Cheapest
Bus
222 Waverly Ave
39 Dalton St
Fastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Next departures for Syracuse to Boston on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Bus
Amtrak Station
Boston (South Station)
Cheapest
Bus
SYR Airport
39 Dalton St
Fastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Next departures for Syracuse to Boston on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
222 Waverly Ave
39 Dalton St
Cheapest
Bus
SYR Airport
39 Dalton St
Fastest
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Boston (South Station)
No tags
Last refresh of the prices: Today at 11:06 AM EST.
Compare 2 ways to go from Syracuse to Boston
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 10 hours 45 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Syracuse Boston recent customer reviews
My favorite part was when the bus was at the station, they just... didn't have a driver???
2 out of 5 stars
Micah W.
Top rating because the driver was loud and clear in his announcing, there was ample room and
comfortable seating, safety issue regarding head light area was caught, and the replaced bus was
newer with working plugs and even roomier and more comfortable!
5 out of 5 stars
Joseph P.
As buses go it was fine. They had us change buses before we ever left the first station. The second bus had very little leg room. Overall it was a typical bus trip.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
With about 2 daily trips between Syracuse and Boston, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.
Based on 1125 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the cleanliness but often complained with the wifi. Adirondack Trailways ticket prices on this trip start at $87
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
700 Atlantic Ave, Boston, MA 02205, USASouth Station
D - Copley Square
115-127 St James Ave, Boston, MA 02116, USA
E - Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
F - Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
Frequently asked questions about traveling from Syracuse, US to Boston, MA, US by bus
What is the travel distance from Syracuse to Boston?
About 263 miles (424 km) separate Syracuse and Boston.
What are the departure and arrival stations when taking the bus from Syracuse to Boston?
The majority of buses traveling from Syracuse to Boston start their journey at Regional Transportation Center and wind up at Back Bay Station. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Boston?
Once in Boston, you can start exploring the city and discover its surroundings. The top sights and things to do are Boston Bruins at TD Garden, Public Garden, North End, Boston Fire Museum and Duck Tour.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/14
$108
11/15
$89
Today
$85
11/17
$60
11/18
$58
11/19
$56
11/20
$56
11/21
$100
The cheapest trip from Syracuse, US to Boston, MA, US was searched and found on Nov 19, 2025 with a price of $56
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Boston, MA, US, as early as possible.
You can expect to pay from $56 to $164 for a bus ticket from Syracuse, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-11-19.
What's the cheapest way to go from Syracuse, US to Boston, MA, US?
The bus is the cheapest travel choice for this destination