Next departures for Syracuse to Philadelphia on November 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Syracuse (Regional Transportation Center)
199 Spring Garden St.
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 3
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Amtrak Station
Philadelphia (Spring Garden)
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 4
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Amtrak Station
Philadelphia (Spring Garden)
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 5
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 6
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Amtrak Station
Philadelphia (Spring Garden)
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 7
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Adirondack Trailways + Peter Pan
Amtrak Station
Philadelphia (Spring Garden)
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 8
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
New York Trailways + Peter Pan
Amtrak Station
Philadelphia (Spring Garden)
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Next departures for Syracuse to Philadelphia on November 9
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Adirondack Trailways + Peter Pan
Amtrak Station
Philadelphia (Spring Garden)
Cheapest
Syracuse (Regional Transportation Center)
199 Spring Garden St.
Fastest
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
199 Spring Garden St.
No tags
Syracuse (Regional Transportation Center)
Philadelphia, 199 Spring Garden St
No tags
Last refresh of the prices: Today at 12:39 AM EDT.
Accepted payments
Compare 2 ways to go from Syracuse to Philadelphia
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Philadelphia. The journey takes about 9 hours and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Syracuse Philadelphia recent customer reviews
The only reason the bus was late is because of the snow and weather issues
Trailways is a network of over 70 bus companies that focus on providing quality bus rides at affordable prices all over the US since 1936. Among the most famous affiliates are Trailways of New York, Pine Hill Trailways, Adirondack Trailways and Burlington Trailways. Trailways buses have WiFi, power outlets, bathrooms, air conditioning, overhead lighting, and reclinable seats with footrests. You can find two different types of Trailway fares: saver and flexible. Saver tickets are non-refundable, while flexible tickets are fully reimbursed up to one hour before travel time. If you're traveling with them, don't forget to print your boarding pass and show a valid photo ID to board the bus.
Based on 1119 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the cleanliness but often complained with the wifi. Adirondack Trailways ticket prices on this trip start at $90
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Syracuse to Philadelphia.
Bus service from Syracuse to Philadelphia will be provided by the most trusted bus companies.
Discover how much the bus trip from Syracuse to Philadelphia will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Syracuse and Philadelphia?
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USAIndependence Travel Center
C - #2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D - Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
E - Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
F - NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Frequently asked questions for your trip Syracuse, US - Philadelphia, PA
What is the travel distance from Syracuse to Philadelphia?
Syracuse and Philadelphia are 220 miles (355 km) apart.
What are the departure and arrival stations when taking the bus from Syracuse to Philadelphia?
The majority of buses traveling from Syracuse to Philadelphia start their journey at Regional Transportation Center and wind up at Philadelphia Airport. These are the primary departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Philadelphia?
Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Eastern State Penitentiary, Please Touch Museum, Betsy Ross House, The Franklin Institute and Liberty Bell.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
10/31
$99
11/01
$108
Today
$111
11/03
$98
11/04
$65
11/05
$59
11/06
$69
11/07
$73
The cheapest trip from Syracuse, US to Philadelphia, PA was searched and found on Nov 5, 2025 with a price of $59
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Philadelphia, PA, as early as possible.
You can expect to pay from $59 to $187 for a bus ticket from Syracuse, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-11-05.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Syracuse to Philadelphia but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Syracuse to Philadelphia, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Syracuse to Philadelphia will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Syracuse to Philadelphia.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
What's the cheapest way to go from Syracuse, US to Philadelphia, PA?
The bus is the cheapest travel choice for this destination
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
The cheapest trip from Syracuse, US to Philadelphia, PA was searched and found on Nov 5, 2025 with a price of $59
The bus is the cheapest travel choice for this destination
