Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Portsmouth | CheapestFastest | ||||
| Bus | Syracuse (Regional Transportation Center) | Portsmouth | No tags |
Last refresh of the prices: Last Saturday at 1:39 PM EST.
Get from Syracuse to Portsmouth
The journey takes about 13 hours and with fares starting at just $63, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Syracuse, US to Portsmouth, NH, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Portsmouth?
The cheapest bus tickets from Syracuse to Portsmouth start from $63. The average price for this route is around $63. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Portsmouth?
The average bus trip duration from Syracuse to Portsmouth is 13h, covering a distance of 273 miles (440 km). The quickest bus can get you there in 13h and is operated by Greyhound.
Which bus companies service the Syracuse to Portsmouth route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Syracuse to Portsmouth?
The earliest bus departs from Syracuse to Portsmouth at 6:50am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Portsmouth?
A bus trip from Syracuse to Portsmouth generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Portsmouth, NH, US was searched and found on Feb 15, 2026 with a price of $57To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Portsmouth, NH, US, as early as possible.
You can expect to pay from $57 to $77 for a bus ticket from Syracuse, US to Portsmouth, NH, US based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2026-02-20.
