How much is the bus ticket from Wilmington to Florence?

The cheapest bus tickets from Wilmington to Florence start from $68. The average price for this route is around $116. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Wilmington to Florence?

The average bus trip duration from Wilmington to Florence is 16h 15m, covering a distance of 447 miles (721 km). The quickest bus can get you there in 12h 55m and is operated by FlixBus .

Which bus companies service the Wilmington to Florence route?

Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Wilmington to Florence?

The earliest bus departs from Wilmington to Florence at 2:55am. And the latest bus departs at 9:25pm.

What are the CO₂ emissions for the bus trip from Wilmington to Florence?

A bus trip from Wilmington to Florence generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Wilmington to Florence?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11828 reviews.

Which bus company has the best Wi-Fi from Wilmington to Florence?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Wilmington to Florence?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Wilmington to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Wilmington to Florence from $81 | Refundable Tickets

Previously seen trips

Next departures for Wilmington to Florence on January 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	5:00pm	Wilmington Bus Station	1d 12h	5:35am	Florence, SC	No tags
FlixBus + Greyhound	Bus	5:00pm	Wilmington Bus Station	1d 12h	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	9:25pm	Wilmington Bus Station	1d 8h	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	1:50pm	Wilmington Bus Station	16h 45m	6:35am	Florence, SC	No tags
FlixBus + Greyhound	Bus	1:50pm	Wilmington Bus Station	16h 45m	6:35am	Florence, SC	No tags

Compare 2 ways to go from Wilmington to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 10 hours 28 minutes and with fares starting at just $96, it presents an excellent value for a comfortable ride.

1train per day

10h 28mAverage Duration

447 milesDistance

66kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$68 - $271	Average Duration16h 15m	CO₂ emissions 18kg CO₂e
Train	Average Price$96 - $626	Average Duration10h 28m	CO₂ emissions 66kg CO₂e

Where are the popular stops in Wilmington and Florence?

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
Visit page
B
Wilmington Station
100 French St, Wilmington, DE 19801, USA
Visit page
C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511,962 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,490 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Wilmington, DE to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Wilmington to Florence?
The cheapest bus tickets from Wilmington to Florence start from $68. The average price for this route is around $116. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Wilmington to Florence?
The average bus trip duration from Wilmington to Florence is 16h 15m, covering a distance of 447 miles (721 km). The quickest bus can get you there in 12h 55m and is operated by FlixBus.
Which bus companies service the Wilmington to Florence route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Wilmington to Florence?
The earliest bus departs from Wilmington to Florence at 2:55am. And the latest bus departs at 9:25pm.
What are the CO₂ emissions for the bus trip from Wilmington to Florence?
A bus trip from Wilmington to Florence generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Wilmington to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.
Which bus company has the best Wi-Fi from Wilmington to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Wilmington to Florence?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Wilmington to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/06

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01/07

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Today

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01/09

$81

01/10

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01/11

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The cheapest trip from Wilmington, DE to Florence, SC, US was searched and found on Jan 9, 2026 with a price of $81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Florence, SC, US, as early as possible.

You can expect to pay from $81 to $82 for a bus ticket from Wilmington, DE to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $81 which is on 2026-01-09.