Previously seen trips

Next departures for Wilmington to Florence on September 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
Greyhound + FlixBus	Bus Wifi Toilet Power outlets	1:50pm	Wilmington Bus Station	15h 55m	5:45am	Florence, SC
FlixBus + Greyhound	Bus Wifi Toilet Power outlets	1:50pm	Wilmington Bus Station	15h 55m	5:45am	Florence, SC
	Bus Wifi Toilet Power outlets	4:50pm	Newark (DE)	12h 55m	5:45am	Florence, SC
Greyhound + FlixBus	Bus Wifi Toilet Power outlets	5:30pm	Delaware Rest Stop S	19h 15m	12:45pm	Bus station
FlixBus + Greyhound	Bus Wifi Toilet Power outlets	5:30pm	Delaware Rest Stop S	19h 15m	12:45pm	Bus station

Compare 2 ways to go from Wilmington to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 15 hours 49 minutes and with fares starting at just CLP 59,213, it presents an excellent value for a comfortable ride.

9bus per day

15h 49mAverage Duration

444 milesDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCLP 59,213 - CLP 222,645	Average Duration15h 49m	CO₂ emissions 18kg CO₂e
Train	Average PriceCLP 94,944 - CLP 250,863	Average Duration10h 31m	CO₂ emissions 66kg CO₂e

Bus stations and stops in Wilmington and Florence

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
Visit page
B
Amtrak/SEPTA Station
100 French St, Wilmington, DE 19801, USA
Visit page
C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/588,153 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/515,739 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Wilmington, DE to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Wilmington to Florence?
The cheapest bus tickets from Wilmington to Florence start from CLP 59,213. The average price for this route is around CLP 96,135. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Wilmington to Florence?
The average bus trip duration from Wilmington to Florence is 15h 49m, covering a distance of 444 miles (716 km). The quickest bus can get you there in 11h 4m and is operated by Greyhound.
Which bus companies service the Wilmington to Florence route?
Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Wilmington to Florence?
The earliest bus departs from Wilmington to Florence at 12:55am. And the latest bus departs at 9:45pm.
What are the CO₂ emissions for the bus trip from Wilmington to Florence?
A bus trip from Wilmington to Florence generates an estimated 17.8858 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Wilmington to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88134 reviews.
Which bus company has the best Wi-Fi from Wilmington to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Wilmington to Florence?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Wilmington to Florence?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/15

CLP 87,107

09/16

CLP 61,015

Today

CLP 89,568

09/18

No data

09/19

No data

09/20

No data

09/21

No data

09/22

No data

The cheapest trip from Wilmington, DE to Florence, SC, US was searched and found on Sep 16, 2026 with a price of CLP 61,015

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Florence, SC, US, as early as possible.