What is the travel distance from Wilmington to Roanoke?

The distance between the two cities is 292 miles (470 km).

What are the departure and arrival stations when taking the bus from Wilmington to Roanoke?

The majority of buses traveling from Wilmington to Roanoke start their journey at Wilmington Bus Station and wind up at Salem - Exit 140 Park & Ride. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

Bus Wilmington to Roanoke from $45 | Refundable Tickets

Next bus departures

Next departures for Wilmington to Roanoke on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	9:25pm	Wilmington Bus Station	14h 40m	12:05pm	Roanoke Bus Stop	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	6:50pm	Delaware Rest Stop S	17h 15m	12:05pm	Roanoke Bus Stop	No tags

Next departures for Wilmington to Roanoke on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	9:25pm	Wilmington Bus Station	14h 40m	12:05pm	Roanoke Bus Stop	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	2:50am	Newark (DE)	9h 15m	12:05pm	Roanoke Bus Stop	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	6:50pm	Delaware Rest Stop S	17h 15m	12:05pm	Roanoke Bus Stop	No tags

Last refresh of the prices: Last Saturday at 9:07 PM EST.

Compare 2 ways to go from Wilmington to Roanoke

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Roanoke. The journey takes about 7 hours 19 minutes and with fares starting at just $48, it presents an excellent value for a comfortable ride.

2train per day

7h 19mAverage Duration

292 milesDistance

43kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$37 - $153	Average Duration14h 40m	CO₂ emissions 12kg CO₂e
Train	Average Price$48 - $263	Average Duration7h 19m	CO₂ emissions 43kg CO₂e

Where are the popular stops in Wilmington and Roanoke?

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
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B
Wilmington Station
100 French St, Wilmington, DE 19801, USA
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C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Stops in Roanoke

A
Salem - Exit 140 Park & Ride
Exit 140 (Park and Ride), Virginia 24153, USA
Visit page

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Wilmington, DE to Roanoke by bus

What is the travel distance from Wilmington to Roanoke?
What are the departure and arrival stations when taking the bus from Wilmington to Roanoke?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

$94

11/23

$120

Today

$105

11/25

$96

11/26

$79

11/27

No data

11/28

No data

11/29

$112

The cheapest trip from Wilmington, DE to Roanoke was searched and found on Nov 26, 2025 with a price of $79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Roanoke, as early as possible.

You can expect to pay from $79 to $120 for a bus ticket from Wilmington, DE to Roanoke based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-11-26.