Bus Tickets from Winston-Salem, NC to Jacksonville, FL

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TodayMay 18
from $100
TomorrowMay 19
from $83
TueMay 20
from $83
WedMay 21
from $94
ThuMay 22
from $87
FriMay 23
SatMay 24
SunMay 25

Next departures to Jacksonville

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 19 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: May 20 at
    Destination city: Jacksonville
    Destination location: Jacksonville Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 19 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: May 19 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: May 20 at
    Destination city: Jacksonville
    Destination location: Jacksonville Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: May 19 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Winston-Salem
    Departure location: Winston-Salem (State University), NC
    Arrival time: May 20 at
    Destination city: Jacksonville
    Destination location: Jacksonville Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Accepted payments

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Bus Winston-Salem to Jacksonville: Trip Overview

Average ticket price$150
Average bus trip duration14h 50m
Number of daily buses2
Earliest bus departure7:10am
Distance407 miles (655 km)
Latest bus departure6:15pm

Winston-Salem to Jacksonville Bus

Busbud helps you find a bus from Winston-Salem to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Winston-Salem to Jacksonville will be provided by the most trusted bus companies.

Discover how much the bus trip from Winston-Salem to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Winston-Salem - Jacksonville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/16
No data
05/17
$94
Today
No data
05/19
$83
05/20
$83
05/21
$94
05/22
$153
05/23
$111
busbud logoThe cheapest trip from Winston-Salem to Jacksonville was searched and found on May 19, 2025 with a price of $83

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Jacksonville, as early as possible.

You can expect to pay from $83 to $477 for a bus ticket from Winston-Salem to Jacksonville based on the last 2 days. You can expect to find the cheapest price for the trip at $83 which is on 2025-05-19.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Winston-Salem and Jacksonville!

Much more than a mere vehicle taking you from Winston-Salem to Jacksonville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Winston-Salem to Jacksonville will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Winston-Salem to Jacksonville while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Winston-Salem by bus?

Bus from Winston-Salem to Jacksonville

You can also go to Jacksonville by train

Train from Winston-Salem to Jacksonville

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