- Winston-Salem to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Winston Salem Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Winston Salem Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Winston Salem Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Winston Salem Greyhound Bus Station | Knoxville Bus Station | No tags |
Get from Winston-Salem to Knoxville
The journey takes about 11 hours 30 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Where are the popular stops in Winston-Salem and Knoxville?
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Winston-Salem to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Winston-Salem to Knoxville?
The cheapest bus tickets from Winston-Salem to Knoxville start from $99. The average price for this route is around $113. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Winston-Salem to Knoxville?
The average bus trip duration from Winston-Salem to Knoxville is 11h 30m, covering a distance of 203 miles (327 km). The quickest bus can get you there in 11h 30m and is operated by Greyhound.
Which bus companies service the Winston-Salem to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Winston-Salem to Knoxville?
The earliest bus departs from Winston-Salem to Knoxville at 10:20am. And the latest bus departs at 10:20am.
What are the CO₂ emissions for the bus trip from Winston-Salem to Knoxville?
A bus trip from Winston-Salem to Knoxville generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






