Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | South Station (Train Terminal) | Greenville Station | Cheapest | ||||
NextGen Acela + Amtrak | Train | Boston Route 128, MA | Greenville Station | Fastest | ||||
| Train | South Station (Train Terminal) | Greenville Station | No tags | ||||
NextGen Acela + Amtrak | Train | South Station (Train Terminal) | Greenville Station | No tags | ||||
| Train | South Station (Train Terminal) | Greenville Station | No tags |
Last refresh of the prices: Yesterday at 8:07 PM EDT.
Compare 2 ways to go from Boston to Greenville
Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 22 hours 10 minutes and with fares starting at just PEN 304, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5791 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at PEN 669
Frequently asked questions about traveling from Boston, MA, US to Greenville, SC by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Boston to Greenville?
The cheapest train tickets from Boston to Greenville start from PEN 669. The average price for this train route is around PEN 1,131. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Boston to Greenville?
The average train ride duration from Boston to Greenville is 20h 29m, covering a distance of 796 miles (1284 km). The quickest train can get you there in 20h 29m and is operated by Amtrak.
Which train operators service the Boston to Greenville route?
Several major train operators operate on this route with 5 trains available per day.
What is the earliest and latest departure time for the train from Boston to Greenville?
The earliest train departs from Boston to Greenville at 8:12am. And the latest train departs at 9:25am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on Apr 28, 2026 with a price of PEN 642To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Greenville, SC, as early as possible.
You can expect to pay from PEN 642 to PEN 3,416 for a train ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at PEN 1,697 which is on 2026-04-30.
