How much is the bus ticket from Harrisburg to Florence?

The cheapest bus tickets from Harrisburg to Florence start from $108. The average price for this route is around $169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Harrisburg to Florence?

The average bus trip duration from Harrisburg to Florence is 20h 55m, covering a distance of 448 miles (722 km). The quickest bus can get you there in 17h 20m and is operated by FlixBus .

Which bus companies service the Harrisburg to Florence route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Harrisburg to Florence?

The earliest bus departs from Harrisburg to Florence at 12:30pm. And the latest bus departs at 11:20pm.

What are the CO₂ emissions for the bus trip from Harrisburg to Florence?

A bus trip from Harrisburg to Florence generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Harrisburg to Florence?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87463 reviews.

Which bus company has the best Wi-Fi from Harrisburg to Florence?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Harrisburg to Florence?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Harrisburg to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Harrisburg to Florence from $137 | Refundable Tickets

Previously seen trips

Next departures for Harrisburg to Florence on December 31
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	10:20am	Harrisburg Bus Station	19h 15m	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	8:50pm	Harrisburg Bus Station	1d 8h	5:35am	Florence, SC	No tags
FlixBus + Greyhound	Bus	10:25am	Harrisburg Bus Station	19h 10m	5:35am	Florence, SC	No tags
FlixBus + Greyhound	Bus	10:25am	Harrisburg Bus Station	19h 10m	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	10:25am	Harrisburg Bus Station	19h 10m	5:35am	Florence, SC	No tags

Compare 2 ways to go from Harrisburg to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 14 hours 5 minutes and with fares starting at just $135, it presents an excellent value for a comfortable ride.

1train per day

14h 5mAverage Duration

447 milesDistance

66kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$108 - $286	Average Duration20h 55m	CO₂ emissions 18kg CO₂e
Train	Average Price$135 - $699	Average Duration14h 5m	CO₂ emissions 66kg CO₂e

Where are the popular stops in Harrisburg and Florence?

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/587,466 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,836 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Harrisburg to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Harrisburg to Florence?
The cheapest bus tickets from Harrisburg to Florence start from $108. The average price for this route is around $169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Florence?
The average bus trip duration from Harrisburg to Florence is 20h 55m, covering a distance of 448 miles (722 km). The quickest bus can get you there in 17h 20m and is operated by FlixBus.
Which bus companies service the Harrisburg to Florence route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Harrisburg to Florence?
The earliest bus departs from Harrisburg to Florence at 12:30pm. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Florence?
A bus trip from Harrisburg to Florence generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Harrisburg to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Harrisburg to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Harrisburg to Florence?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.