Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | BILOXI | Opelika (4th Street Station) | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | BILOXI | Opelika (4th Street Station) | No tags |
Last refresh of the prices: Today at 9:30 AM CST.
Get from Biloxi to Opelika
The journey takes about 4 hours 45 minutes, and with fares starting at just $76, it presents an excellent value for a comfortable ride.
Where are the popular stops in Biloxi and Opelika?
Stops in Biloxi
- A11332 Cedar Lake Rd, Biloxi, MS 39532, USA
- B
Transit Center
820 Dr Martin Luther King Jr Blvd, Biloxi, MS 39530, USA
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
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Frequently asked questions about travelling from Biloxi to Opelika by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Biloxi to Opelika?
The cheapest bus tickets from Biloxi to Opelika start from $76. The average price for this route is around $81. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Biloxi to Opelika?
The average bus travel time from Biloxi to Opelika is 4h 45m, covering a distance of 419 km. The quickest bus can get you there in 4h 10m and is operated by Tornado Bus.
Which bus companies service the Biloxi to Opelika route?
Several major bus companies operate on this route with 4 buses available per day, including services from Tornado Bus, Greyhound.
What are the earliest and latest departure times for the bus from Biloxi to Opelika?
The earliest bus departs from Biloxi to Opelika at 12:59am. And the latest bus departs at 9:55am.
What are the CO₂ emissions for the bus trip from Biloxi to Opelika?
A bus trip from Biloxi to Opelika generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Biloxi to Opelika?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.
Which bus company has the best Wi-Fi from Biloxi to Opelika?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.9.
Which bus company has the best on-time performance from Biloxi to Opelika?
According to Busbud traveller reviews, the most punctual bus company on this route is Tornado Bus, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from Biloxi to Opelika?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Biloxi to Opelika was searched and found on Feb 12, 2026 with a price of $70To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Biloxi to Opelika, as early as possible.
You can expect to pay from $70 to $238 for a bus ticket from Biloxi to Opelika based on the last 2 days. You can expect to find the cheapest price for the trip at $70 which is on 2026-02-12.
