Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | DENVER | Tupelo (Brothers Quick Stop) | CheapestFastest | ||||
 | Bus | DENVER | Tupelo (Brothers Quick Stop) | No tags |
Last refresh of the prices: Yesterday at 5:03 PM MST.
Get from Denver to Tupelo
The journey takes about 1 day, 2 hours 40 minutes, and with fares starting at just $140, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87461 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $142
Frequently asked questions about travelling from Denver to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Denver to Tupelo?
The cheapest bus tickets from Denver to Tupelo start from $140. The average price for this route is around $142. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Denver to Tupelo?
The average bus travel time from Denver to Tupelo is 1d 2h, covering a distance of 1571 km. The quickest bus can get you there in 1d 13h and is operated by Greyhound.
Which bus companies service the Denver to Tupelo route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Denver to Tupelo?
The earliest bus departs from Denver to Tupelo at 7:25pm. And the latest bus departs at 8:10pm.
What are the CO₂ emissions for the bus trip from Denver to Tupelo?
A bus trip from Denver to Tupelo generates an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Denver to Tupelo was searched and found on Dec 31, 2025 with a price of $257To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Tupelo, as early as possible.
You can expect to pay from $257 to $257 for a bus ticket from Denver to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at $257 which is on 2025-12-31.
