Next departures for Florence to Baltimore on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Bus station
Baltimore Downtown Bus Station
No tags
Greyhound + FlixBus
Bus
Bus station
Baltimore
No tags
Bus
2301 W Lucas St.
O'Donnell St. & Travel Plaza, Infront of TA Gas station
No tags
Bus
2301 W Lucas St.
O'Donnell St. & Travel Plaza, Infront of TA Gas station
No tags
Bus
Florence, SC
Baltimore
No tags
Compare 2 ways to go from Florence to Baltimore
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Baltimore. The journey takes about 10 hours 15 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.
Wanda Coach is one of the main Chinatown bus carriers in the US, connecting about 75 cities around the country with inexpensive tickets and comfortable bus rides. Wanda Coach buses travel between Chinatown neighborhoods with direct buses that are affordable, safe and have convenient pick-up and drop-off locations. If you travel with Wanda Coach, you can reschedule your tickets for a $10 fee up to 2 hours before travel time, and their buses have free WiFi, power outlets and bathrooms.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Florence, SC, US to Baltimore by bus
What is the travel distance from Florence to Baltimore?
The distance separating Florence and Baltimore is 389 miles (627 km).
What are the departure and arrival stations when taking the bus from Florence to Baltimore?
The majority of buses traveling from Florence to Baltimore start their journey at Florence Bus Station and wind up at Baltimore Downtown Bus Station. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Baltimore?
Once in Baltimore, you can start exploring the city and discover its surroundings. The top sights and things to do are Oriole Park at Camden Yard, National Great Blacks In Wax Museum, Fort McHenry National Monument and Historic Shrine, National Aquarium and Fells Point.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
No data
11/19
$84
Today
$100
11/21
$69
11/22
$68
11/23
$84
11/24
No data
11/25
No data
The cheapest trip from Florence, SC, US to Baltimore was searched and found on Nov 22, 2025 with a price of $68
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Baltimore, as early as possible.
You can expect to pay from $68 to $100 for a bus ticket from Florence, SC, US to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2025-11-22.
Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Florence, SC, US to Baltimore?
The bus is the cheapest travel choice for this destination
The cheapest trip from Florence, SC, US to Baltimore was searched and found on Nov 22, 2025 with a price of $68
The bus is the cheapest travel choice for this destination
