Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | 1116 Woodruff Rd | CheapestFastest |
Last refresh of the prices: Yesterday at 7:00 PM EST.
Get from Gainesville to Greenville
The journey takes about 13 hours 55 minutes, and with fares starting at just $138, it presents an excellent value for a comfortable ride.
Where are the popular stops in Gainesville and Greenville?
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
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Frequently asked questions about travelling from Gainesville, FL to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Gainesville to Greenville?
The cheapest bus tickets from Gainesville to Greenville start from $138. The average price for this route is around $184. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Greenville?
The average bus travel time from Gainesville to Greenville is 13h 55m, covering a distance of 577 km. The quickest bus can get you there in 9h 35m and is operated by FlixBus.
Which bus companies service the Gainesville to Greenville route?
What are the earliest and latest departure times for the bus from Gainesville to Greenville?
The earliest bus departs from Gainesville to Greenville at 1:10am. And the latest bus departs at 5:00pm.
What are the CO₂ emissions for the bus trip from Gainesville to Greenville?
A bus trip from Gainesville to Greenville generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Gainesville to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which bus company has the best Wi-Fi from Gainesville to Greenville?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Gainesville to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Gainesville to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Greenville, SC was searched and found on Dec 14, 2025 with a price of $187To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Greenville, SC, as early as possible.
