How much is the bus ticket from Gainesville to Greenville?

The cheapest bus tickets from Gainesville to Greenville start from $98. The average price for this route is around $131. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Gainesville to Greenville?

The average bus trip duration from Gainesville to Greenville is 13h 55m, covering a distance of 358 miles (577 km). The quickest bus can get you there in 9h 35m and is operated by FlixBus .

Which bus companies service the Gainesville to Greenville route?

Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus , Greyhound , Amtrak .

What is the earliest and latest departure time for the bus from Gainesville to Greenville?

The earliest bus departs from Gainesville to Greenville at 1:10am. And the latest bus departs at 5:00pm.

What are the CO₂ emissions for the bus trip from Gainesville to Greenville?

A bus trip from Gainesville to Greenville generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Gainesville to Greenville?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5627 reviews.

Which bus company has the best Wi-Fi from Gainesville to Greenville?

Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company has the most timely service from Gainesville to Greenville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Gainesville to Greenville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus Gainesville to Greenville from $132 | Refundable Tickets

Previously seen trips

Next departures for Gainesville to Greenville on December 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	12:30pm	Gainesville Bus Stop	9h 40m	10:10pm	1116 Woodruff Rd	No tags
	Bus	3:20pm	Gainesville Bus Stop	16h 15m	7:35am	1116 Woodruff Rd	No tags
	Bus	4:05pm	Gainesville Bus Stop	18h 35m	10:40am	1116 Woodruff Rd	No tags
FlixBus + Greyhound	Bus	5:35pm	Rosa Parks Station	14h	7:35am	1116 Woodruff Rd	No tags
Greyhound + FlixBus	Bus	5:35pm	Rosa Parks Station	14h	7:35am	1116 Woodruff Rd	No tags

Get from Gainesville to Greenville

This route is served by bus only

The journey takes about 13 hours 55 minutes and with fares starting at just $98, it presents an excellent value for a comfortable ride.

5bus per day

13h 55mAverage Duration

358 milesDistance

14kgCO₂ emissions

Where are the popular stops in Gainesville and Greenville?

Stops in Gainesville

A
Rosa Parks Station
700 SE 3rd St, Gainesville, FL 32601
Visit page
B
Williston Rd & I-75
3509 SW Williston Rd, Gainesville, FL 32608, USA
Visit page
C
Greyhound Station
101 NE 23rd Ave, Gainesville, FL 32609
Visit page

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Compare bus companies

FlixBus

3.5/511,602 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,430 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Amtrak

4/55,643 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Gainesville, FL to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Gainesville to Greenville?
The cheapest bus tickets from Gainesville to Greenville start from $98. The average price for this route is around $131. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Greenville?
The average bus trip duration from Gainesville to Greenville is 13h 55m, covering a distance of 358 miles (577 km). The quickest bus can get you there in 9h 35m and is operated by FlixBus.
Which bus companies service the Gainesville to Greenville route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, Greyhound, Amtrak.
What is the earliest and latest departure time for the bus from Gainesville to Greenville?
The earliest bus departs from Gainesville to Greenville at 1:10am. And the latest bus departs at 5:00pm.
What are the CO₂ emissions for the bus trip from Gainesville to Greenville?
A bus trip from Gainesville to Greenville generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Gainesville to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which bus company has the best Wi-Fi from Gainesville to Greenville?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Gainesville to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Gainesville to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/11

No data

12/12

No data

Today

No data

12/14

$132

12/15

No data

12/16

No data

12/17

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12/18

No data

The cheapest trip from Gainesville, FL to Greenville, SC was searched and found on Dec 14, 2025 with a price of $132

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Greenville, SC, as early as possible.

You can expect to pay from $132 to $132 for a bus ticket from Gainesville, FL to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $132 which is on 2025-12-14.