How much is the bus ticket from Jacksonville to St. Louis?

The cheapest bus tickets from Jacksonville to St. Louis start from $195. The average price for this route is around $263. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Jacksonville to St. Louis?

The average bus travel time from Jacksonville to St. Louis is 1d , covering a distance of 1208 km. The quickest bus can get you there in 19h 30m and is operated by FlixBus .

Which bus companies service the Jacksonville to St. Louis route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from Jacksonville to St. Louis?

The earliest bus departs from Jacksonville to St. Louis at 9:30am. And the latest bus departs at 10:05pm.

What are the CO₂ emissions for the bus trip from Jacksonville to St. Louis?

A bus trip from Jacksonville to St. Louis generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Jacksonville to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87463 reviews.

Which bus company has the best Wi-Fi from Jacksonville to St. Louis?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Jacksonville to St. Louis?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Jacksonville to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Jacksonville to St. Louis from $180 | Refundable Tickets

Next bus departures

Next departures for Jacksonville to St. Louis on January 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:05pm	Jacksonville Bus Station	1d 12h	9:10am	Gateway Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	19h 30m	3:55pm	Gateway Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	1d	9:10am	Gateway Station	No tags

Next departures for Jacksonville to St. Louis on January 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	19h 30m	3:55pm	Gateway Station	Cheapest
	Bus	4:30pm	Jacksonville Bus Station	17h 40m	9:10am	Gateway Station	Fastest

Next departures for Jacksonville to St. Louis on January 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	4:30pm	Jacksonville Bus Station	17h 40m	9:10am	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	19h 30m	3:55pm	Gateway Station	No tags

Last refresh of the prices: Last Wednesday at 3:23 AM EST.

Compare 2 ways to go from Jacksonville to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 40 minutes, and with fares starting at just $195, it presents an excellent value for a comfortable ride.

3bus per day

1d Average Duration

1208 kmDistance

30kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$195 - $427	Average Duration1d	CO₂ emissions 30kg CO₂e
Train	Average Price$311 - $4,043	Average Duration2d	CO₂ emissions 109kg CO₂e

Where are the popular stops in Jacksonville and St. Louis?

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page Map
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
Map
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
Map
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Map

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page Map

Compare bus companies

Greyhound

3.5/587,494 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/512,005 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Jacksonville, FL to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to St. Louis?
The cheapest bus tickets from Jacksonville to St. Louis start from $195. The average price for this route is around $263. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to St. Louis?
The average bus travel time from Jacksonville to St. Louis is 1d , covering a distance of 1208 km. The quickest bus can get you there in 19h 30m and is operated by FlixBus.
Which bus companies service the Jacksonville to St. Louis route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Jacksonville to St. Louis?
The earliest bus departs from Jacksonville to St. Louis at 9:30am. And the latest bus departs at 10:05pm.
What are the CO₂ emissions for the bus trip from Jacksonville to St. Louis?
A bus trip from Jacksonville to St. Louis generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Jacksonville to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Jacksonville to St. Louis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Jacksonville to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-09

No data

01-10

No data

Today

No data

01-12

$185

01-13

No data

01-14

No data

01-15

$204

01-16

$204

The cheapest trip from Jacksonville, FL to St. Louis was searched and found on Jan 12, 2026 with a price of $185

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to St. Louis, as early as possible.

You can expect to pay from $185 to $204 for a bus ticket from Jacksonville, FL to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $185 which is on 2026-01-12.