How far is Orlando from Key West?

Orlando and Key West are 445 km (276 miles) apart.

What are the departure and arrival locations for buses traveling from Orlando to Key West?

Buses departing from Orlando Bus Station in Orlando will take you to Caroline St in Key West.

Bus Orlando to Key West from $65 | Refundable Tickets

Next bus departures

Next departures for Orlando to Key West on November 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	10:35pm	Orlando Bus Station	10h 55m	9:30am	Key West Bus Station	CheapestFastest

Next departures for Orlando to Key West on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:35pm	Orlando Bus Station	10h 55m	9:30am	Key West Bus Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	6:05am	The Florida Mall	9h 25m	3:30pm	Key West Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	5:30am	Orlando Bus Station	10h	3:30pm	Key West Bus Station	No tags

Next departures for Orlando to Key West on November 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:35pm	Orlando Bus Station	10h 55m	9:30am	Key West Bus Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	6:05am	The Florida Mall	9h 25m	3:30pm	Key West Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	5:30am	Orlando Bus Station	10h	3:30pm	Key West Bus Station	No tags

Next departures for Orlando to Key West on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	6:05am	The Florida Mall	9h 25m	3:30pm	Key West Bus Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	5:30am	Orlando Bus Station	10h	3:30pm	Key West Bus Station	No tags
	Bus	10:35pm	Orlando Bus Station	10h 55m	9:30am	Key West Bus Station	No tags

Next departures for Orlando to Key West on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	5:30am	Orlando Bus Station	10h	3:30pm	Key West Bus Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	6:05am	The Florida Mall	9h 25m	3:30pm	Key West Bus Station	Fastest
	Bus	10:35pm	Orlando Bus Station	10h 55m	9:30am	Key West Bus Station	No tags

Last refresh of the prices: Yesterday at 11:43 AM EST.

Get from Orlando to Key West

This route is served by bus only

The journey takes about 10 hours, and with fares starting at just $68, it presents an excellent value for a comfortable ride.

3bus per day

10hAverage Duration

435 kmDistance

11kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,386 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87386 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $68

Greyhound Orlando Key West recent customer reviews

Overall very unhappy with this trip. Bus was 2 hours late, staff on the bus, driver was courteous but the other “helper” was rude and no help at all. I asked him for options or ideas so I could make it down to Key West on time for an appointment and he couldn’t be bothered, even though he was just sitting in the front doing nothing. Because the bus was 2 hours late getting to Miami, I missed my bus to Key West. The staff at Miami was extremely slow and I found a shuttle in the meantime to take me there instead so I could make my appointment.

Derek S.

November 16, 2018

Good journey

Denise B.

December 17, 2019

Great bus driver all the way to key West

Donald C.

March 26, 2019

FlixBus

3.5/511,384 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Orlando and Key West?

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Stops in Key West

A
Caroline St
908 Caroline St, Key West, FL 33040, USA
Visit page
B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA

Frequently asked questions about travelling from Orlando to Key West by bus

How far is Orlando from Key West?
Orlando and Key West are 445 km (276 miles) apart.
What are the departure and arrival locations for buses traveling from Orlando to Key West?
Buses departing from Orlando Bus Station in Orlando will take you to Caroline St in Key West.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-18

$123

11-19

$113

Today

$116

11-21

$136

11-22

$105

11-23

No data

11-24

$97

11-25

$104

The cheapest trip from Orlando to Key West was searched and found on Nov 24, 2025 with a price of $97

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Key West, as early as possible.

You can expect to pay from $97 to $136 for a bus ticket from Orlando to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-11-24.