Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Orlando Key West recent customer reviews
Overall very unhappy with this trip. Bus was 2 hours late, staff on the bus, driver was courteous but the other “helper” was rude and no help at all. I asked him for options or ideas so I could make it down to Key West on time for an appointment and he couldn’t be bothered, even though he was just sitting in the front doing nothing.
Because the bus was 2 hours late getting to Miami, I missed my bus to Key West. The staff at Miami was extremely slow and I found a shuttle in the meantime to take me there instead so I could make my appointment.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Orlando to Key West by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Key West?
The cheapest bus tickets from Orlando to Key West start from $52. The average price for this route is around $80. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Key West?
The average bus trip duration from Orlando to Key West is 10h, covering a distance of 277 miles (446 km). The quickest bus can get you there in 10h 25m and is operated by FlixBus.
Which bus companies service the Orlando to Key West route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Orlando to Key West?
The earliest bus departs from Orlando to Key West at 12:45am. And the latest bus departs at 10:35pm.
What are the CO₂ emissions for the bus trip from Orlando to Key West?
A bus trip from Orlando to Key West generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Orlando to Key West?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Orlando to Key West?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Orlando to Key West?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Key West?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/01
$104
12/02
$74
Today
$73
12/04
$78
12/05
$64
12/06
$64
12/07
$59
12/08
$53
The cheapest trip from Orlando to Key West was searched and found on Dec 8, 2025 with a price of $53
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Key West, as early as possible.
You can expect to pay from $53 to $104 for a bus ticket from Orlando to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-12-08.
The cheapest trip from Orlando to Key West was searched and found on Dec 8, 2025 with a price of $53
