Bus Tickets from San Diego (CA), US to San Luis Obispo

Find affordable bus tickets from San Diego (CA), US to San Luis Obispo with flexible options. Book your trip now

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ThuJun 12
from US$70
FriJun 13
from US$65
SatJun 14
from US$89
SunJun 15
from US$65
MonJun 16
from US$65
TueJun 17
from US$65
WedJun 18
ThuJun 19

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 13 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: June 13 at
    Destination city: San Luis Obispo
    Destination location: San Luis Obispo
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 7:44 PM PDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from San Diego to San Luis Obispo

Average PriceUS$34 - US$155Average Duration8h 35m
10kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$65 - US$65Average Duration8h 38m
39kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Diego to San Luis Obispo

Among the sustainable travel choices, the bus stands out as a good way to reach San Luis Obispo. The journey takes about 8 hours 35 minutes, and with fares starting at just US$34, it presents an excellent value for a comfortable ride.

2bus per day
8h 35mAverage Duration
US$34Cheapest ticket
10kgCO₂ emissions

Bus San Diego to San Luis Obispo: Trip Overview

Average Ticket PriceUS$55
Average Bus Trip Duration8h 35m
Number of daily buses2
Earliest bus departure5:15am
Distance413 km
Latest bus departure9:25pm

San Diego to San Luis Obispo Bus

Busbud helps you find a bus from San Diego to San Luis Obispo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from San Diego to San Luis Obispo will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from San Diego to San Luis Obispo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego (CA), US - San Luis Obispo

  1. How long is the trip from San Diego to San Luis Obispo by bus?

    The bus ride from San Diego to San Luis Obispo takes 8h 35m, on average. The fastest bus on this trip will get to San Luis Obispo in 7h 55m

  2. What is the travel distance from San Diego to San Luis Obispo?

    San Diego and San Luis Obispo are 426 km (264 miles) apart.

  3. What are the departure and arrival locations for buses traveling from San Diego to San Luis Obispo?

    Buses departing from Mission Valley Sheraton in San Diego will take you to AMTRAK Station in San Luis Obispo.

  4. What is the cheapest way to get from San Diego to San Luis Obispo?

    Taking the bus is the most budget-friendly option to travel from San Diego to San Luis Obispo. With a starting ticket price of US$34, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from San Diego to San Luis Obispo?

    The bus from San Diego to San Luis Obispo will cost you US$55, on average.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-08
US$84
06-09
US$84
Today
US$84
06-11
US$84
06-12
US$84
06-13
US$84
06-14
US$84
06-15
US$84
busbud logoThe cheapest trip from San Diego to San Luis Obispo was searched and found on Jun 8, 2025 with a price of US$84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to San Luis Obispo, as early as possible.

You can expect to pay from US$84 to US$84 for a bus ticket from San Diego to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at US$84 which is on 2025-06-11.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and San Luis Obispo!

Much more than a mere vehicle taking you from San Diego to San Luis Obispo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to San Luis Obispo that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to San Luis Obispo.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from San Diego to San Luis Obispo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego by bus?

Bus from San Diego to San Luis Obispo

You can also go to San Luis Obispo by train

Train from San Diego to San Luis Obispo

Why choose Busbud?

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