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- This trip is recommended because it is the: Cheapest + Fastest
- Departure time: June 15 atDeparture city: San DiegoDeparture location: Santa Fe DepotArrival time: June 16 atDestination city: San Luis ObispoDestination location: AMTRAK StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: June 15 atDeparture city: San DiegoDeparture location: Santa Fe DepotArrival time: June 16 atDestination city: San Luis ObispoDestination location: Cal Poly Vista Grande Dining ComplexOperated by: AmtrakVehicle: BusDuration:
Last refresh of the prices: Yesterday at 9:54 PM PDT.
Prices and availability are subject to change.
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Compare 2 ways to go from San Diego to San Luis Obispo
Busbud recommends taking the bus from San Diego to San Luis ObispoAmong the sustainable travel choices, the bus stands out as a good way to reach San Luis Obispo. The journey takes about 8 hours 35 minutes, and with fares starting at just US$34, it presents an excellent value for a comfortable ride.
Bus San Diego to San Luis Obispo: Trip Overview
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San Diego to San Luis Obispo Bus
Busbud helps you find a bus from San Diego to San Luis Obispo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from San Diego to San Luis Obispo will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from San Diego to San Luis Obispo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Diego and San Luis Obispo?
Frequently asked questions on the trip San Diego (CA), US - San Luis Obispo
How long is the trip from San Diego to San Luis Obispo by bus?
The bus ride from San Diego to San Luis Obispo takes 8h 35m, on average. The fastest bus on this trip will get to San Luis Obispo in 7h 55m
What is the travel distance from San Diego to San Luis Obispo?
San Diego and San Luis Obispo are 426 km (264 miles) apart.
What are the departure and arrival locations for buses traveling from San Diego to San Luis Obispo?
Buses departing from Mission Valley Sheraton in San Diego will take you to AMTRAK Station in San Luis Obispo.
What is the cheapest way to get from San Diego to San Luis Obispo?
Taking the bus is the most budget-friendly option to travel from San Diego to San Luis Obispo. With a starting ticket price of US$34, this bus becomes your top pick for this journey.
How much does the bus ticket cost from San Diego to San Luis Obispo?
The bus from San Diego to San Luis Obispo will cost you US$55, on average.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to San Luis Obispo was searched and found on Jun 16, 2025 with a price of US$61To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to San Luis Obispo, as early as possible.
You can expect to pay from US$61 to US$341 for a bus ticket from San Diego to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at US$61 which is on 2025-06-16.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and San Luis Obispo!
Much more than a mere vehicle taking you from San Diego to San Luis Obispo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to San Luis Obispo that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to San Luis Obispo.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from San Diego to San Luis Obispo?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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