Find coaches from San Diego, CA, US to San Luis Obispo

Next departures

Next departures from San Diego to San Luis Obispo on 10 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Greyhound Bus Stop
San Luis ObispoCheapestFastest
Amtrak
Santa Fe Depot
AMTRAK StationNo tags
Amtrak
Santa Fe Depot
Cal Poly Vista Grande Dining ComplexNo tags

Last refresh of the prices: Yesterday at 21:02 PDT.

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Compare 2 ways to travel from San Diego to San Luis Obispo

Bus
Average priceUS$28 - US$89Average duration9h 5m
11kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$65 - US$65Average duration8h 47m
39kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from San Diego to San Luis Obispo

Among the sustainable travel choices, the bus stands out as a good way to reach San Luis Obispo. The journey takes about 9 hours 5 minutes and with fares starting at just US$28, it presents an excellent value for a comfortable ride.

1bus per day
9h 5mAverage duration
US$28Cheapest ticket
11kgCO₂ emissions

Bus San Diego, CA, US to San Luis Obispo: Trip Overview

Average ticket priceUS$44
Average bus trip duration9h 5m
Number of daily buses1
Earliest bus departure06:45
Distance263 miles
Latest bus departure21:25

San Diego to San Luis Obispo Bus

Busbud helps you find a bus from San Diego to San Luis Obispo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from San Diego to San Luis Obispo will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from San Diego to San Luis Obispo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego, CA, US - San Luis Obispo

  1. How far is San Luis Obispo from San Diego by coach?

    The journey from San Diego to San Luis Obispo by coach covers an approximate distance of 264 miles (426 km).

  2. Is there a way to reach San Luis Obispo from San Diego without flying?

    To travel from San Diego to San Luis Obispo without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/10
US$84
08/10
US$84
Today
US$84
10/10
US$84
11/10
US$84
12/10
US$84
13/10
US$61
14/10
US$61
busbud logoThe cheapest trip from San Diego, CA, US to San Luis Obispo was searched and found on 13 Oct 2025 with a price of US$61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Luis Obispo as early as possible.

You can expect to pay from US$61 to US$265 for a bus ticket from San Diego, CA, US to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at US$61, which is on 2025-10-13.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and San Luis Obispo!

Much more than a mere vehicle taking you from San Diego to San Luis Obispo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to San Luis Obispo that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to San Luis Obispo.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from San Diego, CA, US to San Luis Obispo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego, CA, US by bus?

Bus from San Luis Obispo to San Diego, CA, US

You can also go to San Luis Obispo by train

Train from San Diego, CA, US to San Luis Obispo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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