Next departures to San Diego
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: May 1 atDeparture city: San FranciscoDeparture location: San Francisco Bus StationArrival time: May 1 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: May 1 atDeparture city: San FranciscoDeparture location: 409 Townsend St, SFArrival time: May 2 atDestination city: San DiegoDestination location: UCSD Health La Jolla StationOperated by: FlixBus
Vehicle: BusDuration: - Departure time: May 1 atDeparture city: San FranciscoDeparture location: 409 Townsend St, SFArrival time: May 2 atDestination city: San DiegoDestination location: San Diego (Old Town-FlixBus)Operated by: FlixBusVehicle: BusDuration:
- Departure time: May 1 atDeparture city: San FranciscoDeparture location: San Francisco Bus StationArrival time: May 2 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: May 1 atDeparture city: San FranciscoDeparture location: Mission St & Fremont StArrival time: May 2 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: Amtrak
Vehicle: BusDuration:
Last refresh of the prices: Last Saturday at 6:31 AM PDT.
Prices and availability are subject to change.
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Bus San Francisco to San Diego: Trip Overview
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San Francisco to San Diego Bus
Busbud helps you find a bus from San Francisco to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from San Francisco to San Diego from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from San Francisco to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Francisco and San Diego?
Frequently asked questions on the trip San Francisco - San Diego
How long is the bus trip from San Francisco to San Diego?
The bus ride from San Francisco to San Diego takes 14h 10m, on average. The fastest bus on this trip will get to San Diego in 10h 45m
How far is San Francisco from San Diego?
The distance between San Francisco and San Diego is around 739 km (458 miles).
What are the departure and arrival locations for buses traveling from San Francisco to San Diego?
Buses traveling this route start their trip at Hyde/Beach (Fisherman's Wharf), in San Francisco, and end it at Mission Valley Sheraton, in San Diego.
What is the cheapest way to travel from San Francisco to San Diego?
Taking the bus is the cheapest option to travel from San Francisco to San Diego. With a starting ticket price of US$46, this bus becomes your top pick for this journey.
How much does it cost to take the bus from San Francisco to San Diego?
Taking the bus from San Francisco to San Diego costs on average US$65.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Francisco to San Diego was searched and found on May 5, 2025 with a price of US$40To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco to San Diego, as early as possible.
You can expect to pay from US$40 to US$140 for a bus ticket from San Francisco to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$40 which is on 2025-05-05.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and San Diego!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Francisco to San Diego, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to San Diego that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from San Francisco to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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