Bus Tickets from San Francisco, US to San Diego, CA, US

TodayJul 29
TomorrowJul 30
from $69
ThuJul 31
from $69
FriAug 1
from $69
SatAug 2
from $69
SunAug 3
from $69
MonAug 4
from $63
TueAug 5
from $63

Next departures to San Diego

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 30 at
    Departure city: San Francisco
    Departure location: Mission St & Fremont St
    Arrival time: July 30 at
    Destination city: San Diego
    Destination location: Santa Fe Depot
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 30 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: July 31 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 30 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: July 31 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 30 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: July 30 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 30 at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: July 30 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus San Francisco, US to San Diego, CA, US: Trip Overview

Average ticket price$76
Average bus trip duration13h
Number of daily buses11
Earliest bus departure6:30am
Distance446 miles (718 km)
Latest bus departure11:25pm

San Francisco to San Diego Bus

Busbud helps you find a bus from San Francisco to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from San Francisco to San Diego from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from San Francisco to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Francisco, US - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/27
$65
07/28
$65
Today
$65
07/30
$65
07/31
$65
08/01
$65
08/02
$65
08/03
$65
busbud logoThe cheapest trip from San Francisco, US to San Diego, CA, US was searched and found on Jul 27, 2025 with a price of $65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Diego, CA, US, as early as possible.

You can expect to pay from $65 to $186 for a bus ticket from San Francisco, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $65 which is on 2025-07-30.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and San Diego!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Francisco to San Diego, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to San Diego that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Francisco to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to San Francisco, US by bus?

Bus from San Francisco, US to San Diego, CA, US

You can also go to San Diego, CA, US by train

Train from San Francisco, US to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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