Bus Tickets from Santa Ana, US to San Francisco, US

Next departures

Next departures for Santa Ana to San Francisco on October 15
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Anaheim Regional Transportation Intermodal Center
409 Townsend St, SFCheapest
Greyhound Lines, Inc.
Anaheim Regional Transportation Intermodal Center
San Francisco Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Santa Ana Bus Station
409 Townsend St, SFNo tags
Greyhound Lines, Inc.
Santa Ana Bus Station
San Francisco Bus StationNo tags

Last refresh of the prices: Last Saturday at 11:19 PM PDT.

Accepted payments

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Bus Santa Ana, US to San Francisco, US: Trip Overview

Average Ticket PriceUS$70
Average Bus Trip Duration11h 10m
Number of daily buses7
Earliest bus departure8:45am
Distance607 km
Latest bus departure9:40pm

Santa Ana to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from Santa Ana to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Santa Ana to San Francisco will be provided by the most trusted bus companies.

Discover how much the bus trip from Santa Ana to San Francisco will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Santa Ana, US - San Francisco, US

  1. What is the travel distance from Santa Ana to San Francisco?

    Santa Ana and San Francisco are 609 km (378 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Santa Ana to San Francisco?

    Buses departing from Santa Ana Greyhound Bus Station in Santa Ana will take you to Hyde/Beach (Fisherman's Wharf) in San Francisco.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-11
US$78
10-12
US$168
Today
US$136
10-14
No data
10-15
US$62
10-16
US$158
10-17
No data
10-18
US$47
busbud logoThe cheapest trip from Santa Ana, US to San Francisco, US was searched and found on Oct 18, 2025 with a price of US$47

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to San Francisco, US, as early as possible.

You can expect to pay from US$47 to US$168 for a bus ticket from Santa Ana, US to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$47 which is on 2025-10-18.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santa Ana to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Santa Ana to San Francisco, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santa Ana to San Francisco will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Santa Ana to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Santa Ana, US by bus?

Bus from San Francisco, US to Santa Ana, US

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