Bus Tickets from Santa Ana, US to San Francisco, US

Previously seen trips

Next departures for Santa Ana to San Francisco on November 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
    		Santa Ana Bus Station
    		409 Townsend St, SFNo tags
    Greyhound
      		Santa Ana Bus Station
      		San Francisco Bus StationNo tags
      Greyhound + FlixBus
        		Santa Ana Bus Station
        		409 Townsend St, SFNo tags
        Greyhound
          		Santa Ana Bus Station
          		San Francisco Bus StationNo tags
          FlixBus + Greyhound
            		Anaheim Regional Transportation Intermodal Center
            		409 Townsend St, SFNo tags

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Get from Santa Ana to San Francisco

            This route is served by bus only

            The journey takes about 11 hours 10 minutes and with fares starting at just $50, it presents an excellent value for a comfortable ride.

            7bus per day
            11h 10mAverage Duration
            377 milesDistance
            15kgCO₂ emissions

            Bus Santa Ana, US to San Francisco, US: Trip Overview

            Average ticket price$81
            Average bus trip duration11h 10m
            Number of daily buses7
            Earliest bus departure8:45am
            Distance377 miles (607 km)
            Latest bus departure9:40pm

            Santa Ana to San Francisco Bus

            With Busbud, comparing and booking tickets for a bus from Santa Ana to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            Bus service from Santa Ana to San Francisco will be provided by the most trusted bus companies.

            Discover how much the bus trip from Santa Ana to San Francisco will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions for your trip Santa Ana, US - San Francisco, US

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/01
            $168
            11/02
            $94
            Today
            $53
            11/04
            $48
            11/05
            $50
            11/06
            No data
            11/07
            $63
            11/08
            No data
            busbud logoThe cheapest trip from Santa Ana, US to San Francisco, US was searched and found on Nov 4, 2025 with a price of $48

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to San Francisco, US, as early as possible.

            You can expect to pay from $48 to $168 for a bus ticket from Santa Ana, US to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-11-04.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from Santa Ana to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Much more than a mere vehicle taking you from Santa Ana to San Francisco, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santa Ana to San Francisco will emit less CO2 than a car or an airplane.

            Make a music playlist for your bus ride from Santa Ana to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Will you be returning to Santa Ana, US by bus?

            Bus from San Francisco, US to Santa Ana, US

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

            People from around the world trust Busbud

            ‌

            Popular Buses Connecting Santa Ana

            Buses Leaving from Santa Ana

            Buses Going to Santa Ana

            Popular Buses Connecting San Francisco

            Buses Leaving from San Francisco

            Buses Going to San Francisco